ID CHEY_HELPY Reviewed; 124 AA. AC P71403; O07677; DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot. DT 01-NOV-1997, sequence version 2. DT 11-JUN-2014, entry version 95. DE RecName: Full=Chemotaxis protein CheY homolog; GN Name=cheY; OrderedLocusNames=HP_1067; OS Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter OS pylori). OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; OC Helicobacteraceae; Helicobacter. OX NCBI_TaxID=85962; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 43504 / NCTC 11637 / JCM 7653 / RPH 13487; RA Wren B.W.; RL Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=DSM 4867 / CCUG 17874 / NCTC 11638; RX PubMed=9244252; RA Beier D., Spohn G., Rappuoli R., Scarlato V.; RT "Identification and characterization of an operon of Helicobacter RT pylori that is involved in motility and stress adaptation."; RL J. Bacteriol. 179:4676-4683(1997). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 700392 / 26695; RX PubMed=9252185; DOI=10.1038/41483; RA Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., RA Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., RA Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., RA Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., RA Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., RA Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., RA Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., RA Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., RA Smith H.O., Fraser C.M., Venter J.C.; RT "The complete genome sequence of the gastric pathogen Helicobacter RT pylori."; RL Nature 388:539-547(1997). RN [4] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 43504 / NCTC 11637 / JCM 7653 / RPH 13487; RA Jackson C.J., Pittman M.S., Clayton C.L., McColm A.A., Bagshaw J.A., RA Kelly D.J.; RT "Chemotaxis is essential for virulence in Helicobacter pylori: RT identification of a novel signal transduction protein (CheF) with both RT CheA and CheY domains."; RL Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Involved in the transmission of sensory signals from the CC chemoreceptors to the flagellar motors. CheY seems to regulate the CC clockwise (CW) rotation (By similarity). CC -!- COFACTOR: Binds 1 magnesium ion per subunit (By similarity). CC -!- INTERACTION: CC O25153:C694_01990; NbExp=3; IntAct=EBI-6409045, EBI-6410665; CC -!- SUBCELLULAR LOCATION: Cytoplasm (Potential). CC -!- SIMILARITY: Contains 1 response regulatory domain. CC -!- SEQUENCE CAUTION: CC Sequence=CAA57487.1; Type=Erroneous initiation; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X81897; CAA57487.1; ALT_INIT; Genomic_DNA. DR EMBL; U97567; AAB66375.1; -; Genomic_DNA. DR EMBL; AE000511; AAD08113.1; -; Genomic_DNA. DR EMBL; AF021090; AAD01682.1; -; Genomic_DNA. DR PIR; C64653; C64653. DR RefSeq; NP_207858.1; NC_000915.1. DR RefSeq; YP_006934983.1; NC_018939.1. DR PDB; 3GWG; X-ray; 1.80 A; A=1-124. DR PDB; 3H1E; X-ray; 2.40 A; A=1-124. DR PDB; 3H1F; X-ray; 2.20 A; A=1-124. DR PDB; 3H1G; X-ray; 1.70 A; A=1-124. DR PDBsum; 3GWG; -. DR PDBsum; 3H1E; -. DR PDBsum; 3H1F; -. DR PDBsum; 3H1G; -. DR ProteinModelPortal; P71403; -. DR DIP; DIP-3256N; -. DR IntAct; P71403; 4. DR MINT; MINT-160671; -. DR STRING; 85962.HP1067; -. DR PRIDE; P71403; -. DR EnsemblBacteria; AAD08113; AAD08113; HP_1067. DR GeneID; 13870261; -. DR GeneID; 899603; -. DR KEGG; heo:C694_05515; -. DR KEGG; hpy:HP1067; -. DR PATRIC; 20593473; VBIHelPyl33062_1116. DR eggNOG; COG0784; -. DR KO; K03413; -. DR OMA; ERTPDIN; -. DR OrthoDB; EOG6PKFC7; -. DR BioCyc; HPY:HP1067-MONOMER; -. DR EvolutionaryTrace; P71403; -. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro. DR GO; GO:0005515; F:protein binding; IPI:IntAct. DR GO; GO:0097588; P:archaeal or bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-KW. DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW. DR InterPro; IPR011006; CheY-like_superfamily. DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver. DR Pfam; PF00072; Response_reg; 1. DR SMART; SM00448; REC; 1. DR SUPFAM; SSF52172; SSF52172; 1. DR PROSITE; PS50110; RESPONSE_REGULATORY; 1. PE 1: Evidence at protein level; KW 3D-structure; Chemotaxis; Complete proteome; Cytoplasm; KW Flagellar rotation; Magnesium; Metal-binding; Phosphoprotein; KW Reference proteome; Two-component regulatory system. FT CHAIN 1 124 Chemotaxis protein CheY homolog. FT /FTId=PRO_0000081050. FT DOMAIN 1 120 Response regulatory. FT METAL 7 7 Magnesium (By similarity). FT METAL 8 8 Magnesium (By similarity). FT METAL 53 53 Magnesium (By similarity). FT METAL 55 55 Magnesium; via carbonyl oxygen (By FT similarity). FT MOD_RES 53 53 4-aspartylphosphate (By similarity). FT VARIANT 122 122 T -> A (in strain: NCTC 11637 and NCTC FT 11638). FT STRAND 3 6 FT HELIX 10 22 FT STRAND 28 33 FT HELIX 34 43 FT STRAND 49 52 FT STRAND 57 59 FT HELIX 61 69 FT STRAND 74 76 FT STRAND 79 84 FT HELIX 88 97 FT STRAND 101 105 FT HELIX 109 120 SQ SEQUENCE 124 AA; 13915 MW; F2B40BC0C04FCBFA CRC64; MKLLVVDDSS TMRRIIKNTL SRLGYEDVLE AEHGVEAWEK LDANADTKVL ITDWNMPEMN GLDLVKKVRS DSRFKEIPII MITTEGGKAE VITALKAGVN NYIVKPFTPQ VLKEKLEVVL GTND //