ID CHEY_HELPY Reviewed; 124 AA. AC P71403; O07677; DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot. DT 01-NOV-1997, sequence version 2. DT 16-JUN-2009, entry version 62. DE RecName: Full=Chemotaxis protein cheY homolog; GN Name=cheY; OrderedLocusNames=HP_1067; OS Helicobacter pylori (Campylobacter pylori). OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; OC Helicobacteraceae; Helicobacter. OX NCBI_TaxID=210; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 43504 / NCTC 11637 / JCM 7653 / RPH 13487; RA Wren B.W.; RL Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=DSM 4867 / CCUG 17874 / NCTC 11638; RX MEDLINE=97386403; PubMed=9244252; RA Beier D., Spohn G., Rappuoli R., Scarlato V.; RT "Identification and characterization of an operon of Helicobacter RT pylori that is involved in motility and stress adaptation."; RL J. Bacteriol. 179:4676-4683(1997). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 700392 / 26695; RX MEDLINE=97394467; PubMed=9252185; DOI=10.1038/41483; RA Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., RA Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., RA Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., RA Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., RA Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., RA Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., RA Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., RA Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., RA Smith H.O., Fraser C.M., Venter J.C.; RT "The complete genome sequence of the gastric pathogen Helicobacter RT pylori."; RL Nature 388:539-547(1997). RN [4] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 43504 / NCTC 11637 / JCM 7653 / RPH 13487; RA Jackson C.J., Pittman M.S., Clayton C.L., McColm A.A., Bagshaw J.A., RA Kelly D.J.; RT "Chemotaxis is essential for virulence in Helicobacter pylori: RT identification of a novel signal transduction protein (CheF) with both RT CheA and CheY domains."; RL Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Involved in the transmission of sensory signals from the CC chemoreceptors to the flagellar motors. CheY seems to regulate the CC clockwise (CW) rotation (By similarity). CC -!- COFACTOR: Binds 1 magnesium ion per subunit (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm (Potential). CC -!- SIMILARITY: Contains 1 response regulatory domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X81897; CAA57487.1; ALT_INIT; Genomic_DNA. DR EMBL; U97567; AAB66375.1; -; Genomic_DNA. DR EMBL; AE000511; AAD08113.1; -; Genomic_DNA. DR EMBL; AF021090; AAD01682.1; -; Genomic_DNA. DR PIR; C64653; C64653. DR RefSeq; NP_207858.1; -. DR HSSP; P06143; 1JBE. DR DIP; DIP:3256N; -. DR GeneID; 899603; -. DR GenomeReviews; AE000511_GR; HP_1067. DR KEGG; hpy:HP1067; -. DR NMPDR; fig|85962.1.peg.1054; -. DR TIGR; HP_1067; -. DR HOGENOM; P71403; -. DR OMA; P71403; WNMPGMS. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-KW. DR GO; GO:0000156; F:two-component response regulator activity; IEA:InterPro. DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW. DR GO; GO:0001539; P:ciliary or flagellar motility; IEA:UniProtKB-KW. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. DR GO; GO:0000160; P:two-component signal transduction system (p...; IEA:UniProtKB-KW. DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver. DR Pfam; PF00072; Response_reg; 1. DR ProDom; PD000039; Response_reg; 1. DR SMART; SM00448; REC; 1. DR PROSITE; PS50110; RESPONSE_REGULATORY; 1. PE 3: Inferred from homology; KW Chemotaxis; Complete proteome; Cytoplasm; Flagellar rotation; KW Magnesium; Metal-binding; Phosphoprotein; KW Two-component regulatory system. FT CHAIN 1 124 Chemotaxis protein cheY homolog. FT /FTId=PRO_0000081050. FT DOMAIN 1 120 Response regulatory. FT METAL 7 7 Magnesium (By similarity). FT METAL 8 8 Magnesium (By similarity). FT METAL 53 53 Magnesium (By similarity). FT METAL 55 55 Magnesium; via carbonyl oxygen (By FT similarity). FT MOD_RES 53 53 4-aspartylphosphate (By similarity). FT VARIANT 122 122 T -> A (in strain: NCTC 11637 and NCTC FT 11638). SQ SEQUENCE 124 AA; 13915 MW; F2B40BC0C04FCBFA CRC64; MKLLVVDDSS TMRRIIKNTL SRLGYEDVLE AEHGVEAWEK LDANADTKVL ITDWNMPEMN GLDLVKKVRS DSRFKEIPII MITTEGGKAE VITALKAGVN NYIVKPFTPQ VLKEKLEVVL GTND //