ID CAD10_MOUSE Reviewed; 265 AA. AC P70408; DT 25-NOV-2002, integrated into UniProtKB/Swiss-Prot. DT 01-FEB-1997, sequence version 1. DT 31-OCT-2006, entry version 41. DE Cadherin-10 (T2-cadherin) (Fragment). GN Name=Cdh10; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE. RC STRAIN=C57BL/6; TISSUE=Testis; RX MEDLINE=97033837; PubMed=8879495; RA Munro S.B., Blaschuk O.W.; RT "A comprehensive survey of the cadherins expressed in the testes of RT fetal, immature, and adult mice utilizing the polymerase chain RT reaction."; RL Biol. Reprod. 55:822-827(1996). RN [2] RP NUCLEOTIDE SEQUENCE [MRNA] OF 117-203. RC STRAIN=CBA/J; TISSUE=Thymocyte; RX MEDLINE=96211873; PubMed=8620560; DOI=10.1006/cimm.1996.0123; RA Munro S.B., Duclos A.J., Jackson A.R., Baines M.G., Blaschuk O.W.; RT "Characterization of cadherins expressed by murine thymocytes."; RL Cell. Immunol. 169:309-312(1996). CC -!- FUNCTION: Cadherins are calcium dependent cell adhesion proteins. CC They preferentially interact with themselves in a homophilic CC manner in connecting cells; cadherins may thus contribute to the CC sorting of heterogeneous cell types. CC -!- SUBCELLULAR LOCATION: Membrane; single-pass type I membrane CC protein (Potential). CC -!- DEVELOPMENTAL STAGE: Expressed at all stages of testicular CC development with highest levels found in fetal gonad. CC -!- SIMILARITY: Contains 5 cadherin domains. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U69137; AAB87708.1; -; mRNA. DR Ensembl; ENSMUSG00000022321; Mus musculus. DR MGI; MGI:107436; Cdh10. DR ArrayExpress; P70408; -. DR InterPro; IPR002126; Cadherin. DR InterPro; IPR000233; Cadherin_C_term. DR Pfam; PF01049; Cadherin_C; 1. DR SMART; SM00112; CA; 1. DR PROSITE; PS00232; CADHERIN_1; PARTIAL. DR PROSITE; PS50268; CADHERIN_2; 1. KW Calcium; Cell adhesion; Glycoprotein; Membrane; Transmembrane. FT CHAIN <1 265 Cadherin-10. FT /FTId=PRO_0000126646. FT TOPO_DOM <1 96 Extracellular (Potential). FT TRANSMEM 97 117 Potential. FT TOPO_DOM 118 265 Cytoplasmic (Potential). FT DOMAIN <1 90 Cadherin 5. FT CARBOHYD 18 18 N-linked (GlcNAc...) (Potential). FT NON_TER 1 1 SQ SEQUENCE 265 AA; 29351 MW; 49A15B6C158C5503 CRC64; DDVDRRSFSF SLAAVNPNFT VQDNEDNTAR ILARKNGFNR HEISTYLLPV VISDNDYPIQ SSTGTLTIRV CACDSQGNMQ SCSAEALLLP WPHTGALIAI LLCIIILLVI VVLFAALKEP LILSKEDIRD NIVSYNDEGG GEEDTQAFDI GTLRNPAAIE EKKLRRDIIP ETLFIPRTPT APGNTDVRDF INERLKEHDL DPTAPPYDSL ATYAYEGNDS VAESLSSLES GTTEGDQNYD YLREWGPRFK KLAEMYGGGE SDKDS //