ID COX3_BRALA Reviewed; 262 AA. AC P69215; O47425; DT 15-FEB-2005, integrated into UniProtKB/Swiss-Prot. DT 15-FEB-2005, sequence version 1. DT 26-JUN-2007, entry version 14. DE Cytochrome c oxidase subunit 3 (EC 1.9.3.1) (Cytochrome c oxidase DE polypeptide III). GN Name=COIII; OS Branchiostoma lanceolatum (Common lancelet) (Amphioxus). OG Mitochondrion. OC Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; OC Branchiostoma. OX NCBI_TaxID=7740; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX MEDLINE=98292550; PubMed=9628930; DOI=10.1093/nar/26.13.3279; RA Spruyt N., Delarbre C., Gachelin G., Laudet V.; RT "Complete sequence of the amphioxus (Branchiostoma lanceolatum) RT mitochondrial genome: relations to vertebrates."; RL Nucleic Acids Res. 26:3279-3285(1998). CC -!- FUNCTION: Subunits I, II and III form the functional core of the CC enzyme complex. CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) = 4 ferricytochrome CC c + 2 H(2)O. CC -!- SUBCELLULAR LOCATION: Mitochondrion; mitochondrial inner membrane; CC multi-pass membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 3 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Y16474; CAA76253.1; -; Genomic_DNA. DR PIR; H71390; H71390. DR SMR; P69215; 4-262. DR InterPro; IPR000298; CytC_oxdse_III. DR InterPro; IPR013833; CytC_oxdse_III_a-bundle. DR PANTHER; PTHR11403; CytC_oxdse_III; 1. DR Pfam; PF00510; COX3; 1. DR PROSITE; PS50253; COX3; 1. KW Inner membrane; Membrane; Mitochondrion; Oxidoreductase; KW Transmembrane. FT CHAIN 1 262 Cytochrome c oxidase subunit 3. FT /FTId=PRO_0000183748. SQ SEQUENCE 262 AA; 29711 MW; 6D93D8338AC870D8 CRC64; MTGYQPHPWH LVEPSPWPLV GGSAAFTLTV GLVMWFHYNS ISLMILGLVM IVATMIQWWR DVIREATFQG CHTSYVLSGL RRGMVLFIVS EVFFFLAFFW AFFHSSLAPT VELGVTWPPV GVHPLNAFAV PLLNTAVLLS SGVTVTWAHH ALMEGKRTEA IQSLAITVML GLYFTGLQAW EYYEAPFTIA DSVYGSTFFV ATGFHGLHVI IGSTFLMVCL GRQVFYHYTS SHHFGFEAAA WYWHFVDVVW LFLYVCIYWW GS //