ID HBG_ATEGE STANDARD; PRT; 146 AA. AC P68068; P06891; DT 01-JAN-1988 (Rel. 06, Created) DT 01-JAN-1988 (Rel. 06, Last sequence update) DT 10-MAY-2005 (Rel. 47, Last annotation update) DE Hemoglobin gamma chain. GN Name=HBG; OS Ateles geoffroyi (Black-handed spider monkey). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Platyrrhini; Cebidae; OC Atelinae; Ateles. OX NCBI_TaxID=9509; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=86016820; PubMed=2413451; RA Giebel L.B., van Santen V.L., Slightom J.L., Spritz R.A.; RT "Nucleotide sequence, evolution, and expression of the fetal globin RT gene of the spider monkey Ateles geoffroyi."; RL Proc. Natl. Acad. Sci. U.S.A. 82:6985-6989(1985). RN [2] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=91334472; PubMed=1908094; RA Fitch D.H., Bailey W.J., Tagle D.A., Goodman M., Sieu L., RA Slightom J.L.; RT "Duplication of the gamma-globin gene mediated by L1 long interspersed RT repetitive elements in an early ancestor of simian primates."; RL Proc. Natl. Acad. Sci. U.S.A. 88:7396-7400(1991). RN [3] RP NUCLEOTIDE SEQUENCE. RX PubMed=10222158; DOI=10.1006/mpev.1998.0574; RA Meireles C.M., Czelusniak J., Schneider M.P.C., Muniz J.A.P.C., RA Brigido M.C., Ferreira H.S., Goodman M.; RT "Molecular phylogeny of ateline new world monkeys (Platyrrhini, RT atelinae) based on gamma-globin gene sequences: evidence that RT Brachyteles is the sister group of Lagothrix."; RL Mol. Phylogenet. Evol. 12:10-30(1999). CC -!- FUNCTION: Gamma chains make up the fetal hemoglobin F, in CC combination with alpha chains. CC -!- SUBUNIT: Heterotetramer of two alpha chains and two gamma chains CC in fetal hemoglobin (Hb F). CC -!- TISSUE SPECIFICITY: Red blood cells. CC -!- SIMILARITY: Belongs to the globin family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M36773; AAA36926.1; -; Genomic_DNA. DR EMBL; X53420; CAA37499.1; -; Genomic_DNA. DR EMBL; AF030092; AAB92226.1; -; Genomic_DNA. DR PIR; S21892; HGMKS. DR HSSP; P02096; 1I3D. DR SMR; P68068; 2-146. DR InterPro; IPR002337; Beta_haem. DR InterPro; IPR000971; Globin. DR Pfam; PF00042; Globin; 1. DR PRINTS; PR00814; BETAHAEM. DR PROSITE; PS01033; GLOBIN; 1. KW Erythrocyte; Heme; Iron; Metal-binding; Oxygen transport; Transport. FT INIT_MET 0 0 By similarity. FT METAL 63 63 Iron (heme distal ligand) (By FT similarity). FT METAL 92 92 Iron (heme proximal ligand) (By FT similarity). SQ SEQUENCE 146 AA; 15809 MW; C42EBFA303F2CA17 CRC64; SNFTAEDKAA ITSLWGKVNV EDAGGETLGR LLVVYPWTQR FFDSFGSLSS PSAIMGNPKV KAHGVKVLTS LGEAIKNLDD LKGTFGQLSE LHCDKLHVDP ENFRLLGNVL VTVLAILHGK EFTPEVQASW QKMVAGVASA LASRYH //