ID HBD_SAGNI Reviewed; 146 AA. AC P68015; P02045; DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot. DT 11-OCT-2004, sequence version 1. DT 19-OCT-2011, entry version 36. DE RecName: Full=Hemoglobin subunit delta; DE AltName: Full=Delta-globin; DE AltName: Full=Hemoglobin delta chain; GN Name=HBD; OS Saguinus nigricollis (Black-and-red tamarin). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Platyrrhini; Cebidae; Callitrichinae; Saguinus. OX NCBI_TaxID=9489; RN [1] RP PROTEIN SEQUENCE. RX MEDLINE=72020149; PubMed=4999925; DOI=10.1007/BF00487132; RA Boyer S.H., Crosby E.F., Noyes A.N., Fuller G.F., Leslie S.E., RA Donaldson L.J., Vrablik G.R., Schaefer E.W. Jr., Thurmon T.F.; RT "Primate hemoglobins: some sequences and some proposals concerning the RT character of evolution and mutation."; RL Biochem. Genet. 5:405-448(1971). CC -!- SUBUNIT: Heterotetramer of two delta chains and two alpha chains. CC -!- TISSUE SPECIFICITY: Red blood cells. CC -!- SIMILARITY: Belongs to the globin family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR PIR; E02365; HDMKTB. DR ProteinModelPortal; P68015; -. DR SMR; P68015; 1-146. DR HOVERGEN; HBG009709; -. DR GO; GO:0005833; C:hemoglobin complex; IEA:InterPro. DR GO; GO:0020037; F:heme binding; IEA:InterPro. DR GO; GO:0019825; F:oxygen binding; IEA:InterPro. DR GO; GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. DR InterPro; IPR009050; Globin-like. DR InterPro; IPR012292; Globin_dom. DR InterPro; IPR000971; Globin_subset. DR InterPro; IPR002337; Haemoglobin_b. DR Gene3D; G3DSA:1.10.490.10; Globin_related; 1. DR Pfam; PF00042; Globin; 1. DR PRINTS; PR00814; BETAHAEM. DR SUPFAM; SSF46458; Globin_like; 1. DR PROSITE; PS01033; GLOBIN; 1. PE 1: Evidence at protein level; KW Direct protein sequencing; Heme; Iron; Metal-binding; KW Oxygen transport; Transport. FT CHAIN 1 146 Hemoglobin subunit delta. FT /FTId=PRO_0000053172. FT METAL 63 63 Iron (heme distal ligand). FT METAL 92 92 Iron (heme proximal ligand). FT UNSURE 12 12 A or S. FT UNSURE 16 16 S or G. SQ SEQUENCE 146 AA; 15822 MW; 12174EC83529CCC5 CRC64; VHLTGEEKSA VAALWSKVNV DEVGGEALGR LLVVYPWTQR FFESFGALSS PDAVMGNPKV KAHGKKVLGA FSDGLAHLDN LKGTFAQLSE LHCDKLHVDP ENFRLLGNVL VCVLARNFGK EFTPRVQAAF QKVVAGVATA LAHKYH //