ID DB131_HUMAN Reviewed; 70 AA. AC P59861; DT 26-SEP-2003, integrated into UniProtKB/Swiss-Prot. DT 26-SEP-2003, sequence version 1. DT 31-OCT-2006, entry version 26. DE Beta-defensin 131 precursor (Defensin, beta 131) (Beta-defensin 31) DE (DEFB-31). GN Name=DEFB131; Synonyms=DEFB31; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY. RX MEDLINE=22705149; PubMed=12600824; DOI=10.1165/rcmb.2002-0205OC; RA Kao C.Y., Chen Y., Zhao Y.H., Wu R.; RT "ORFeome-based search of airway epithelial cell-specific novel human RT beta-defensin genes."; RL Am. J. Respir. Cell Mol. Biol. 29:71-80(2003). CC -!- FUNCTION: Has antibacterial activity (Potential). CC -!- SUBCELLULAR LOCATION: Secreted protein (Potential). CC -!- TISSUE SPECIFICITY: Highly expressed in testis. Is moderatly CC expressed in the prostate and small intestine. CC -!- SIMILARITY: Belongs to the beta-defensin family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF529414; AAQ09523.1; -; mRNA. DR UniGene; Hs.590200; -. DR Ensembl; ENSG00000186146; Homo sapiens. DR HGNC; HGNC:18108; DEFB131. DR LinkHub; P59861; -. KW Antibiotic; Antimicrobial; Defensin; Signal. FT SIGNAL 1 22 Potential. FT PEPTIDE 23 70 Beta-defensin 131. FT /FTId=PRO_0000007006. FT DISULFID 29 56 By similarity. FT DISULFID 36 50 By similarity. FT DISULFID 40 57 By similarity. SQ SEQUENCE 70 AA; 8185 MW; 2A3DC1A07FFB6F14 CRC64; MRVLFFVFGV LSLMFTVPPG RSFISNDECP SEYYHCRLKC NADEHAIRYC ADFSICCKLK IIEIDGQKKW //