ID D131_HUMAN STANDARD; PRT; 70 AA. AC P59861; DT 15-SEP-2003 (Rel. 42, Created) DT 15-SEP-2003 (Rel. 42, Last sequence update) DT 15-SEP-2003 (Rel. 42, Last annotation update) DE Beta-defensin 131 precursor (Beta-defensin 31) (DEFB-31). GN DEFB131 OR DEFB31. OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=22705149; PubMed=12600824; RA Kao C.Y., Chen Y., Zhao Y.H., Wu R.; RT "ORFeome-based search of airway epithelial cell-specific novel human RT beta-defensin genes."; RL Am. J. Respir. Cell Mol. Biol. 29:71-80(2003). CC -!- FUNCTION: Has antibacterial activity (Potential). CC -!- SUBCELLULAR LOCATION: Secreted (Potential). CC -!- TISSUE SPECIFICITY: High expressed in testis. Is moderatly CC expressed in the prostate and small intestine. CC -!- SIMILARITY: Belongs to the beta-defensin family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF529414; AAQ09523.1; -. DR Genew; HGNC:18108; DEFB131. KW Antibiotic; Signal. FT SIGNAL 1 22 POTENTIAL. FT CHAIN 23 70 BETA-DEFENSIN 131. FT DISULFID 29 56 BY SIMILARITY. FT DISULFID 36 50 BY SIMILARITY. FT DISULFID 40 57 BY SIMILARITY. SQ SEQUENCE 70 AA; 8185 MW; 2A3DC1A07FFB6F14 CRC64; MRVLFFVFGV LSLMFTVPPG RSFISNDECP SEYYHCRLKC NADEHAIRYC ADFSICCKLK IIEIDGQKKW //