ID   RF1_BUCBP               Reviewed;         362 AA.
AC   P59456;
DT   28-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   28-MAR-2003, sequence version 1.
DT   19-FEB-2014, entry version 75.
DE   RecName: Full=Peptide chain release factor 1;
DE            Short=RF-1;
GN   Name=prfA; OrderedLocusNames=bbp_161;
OS   Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Buchnera.
OX   NCBI_TaxID=224915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bp;
RX   PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA   van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA   Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA   Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT   "Reductive genome evolution in Buchnera aphidicola.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC   -!- FUNCTION: Peptide chain release factor 1 directs the termination
CC       of translation in response to the peptide chain termination codons
CC       UAG and UAA (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- PTM: Methylated by PrmC. Methylation increases the termination
CC       efficiency of RF1 (By similarity).
CC   -!- SIMILARITY: Belongs to the prokaryotic/mitochondrial release
CC       factor family.
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DR   EMBL; AE016826; AAO26894.1; -; Genomic_DNA.
DR   RefSeq; NP_777789.1; NC_004545.1.
DR   ProteinModelPortal; P59456; -.
DR   SMR; P59456; 8-353.
DR   STRING; 224915.bbp161; -.
DR   EnsemblBacteria; AAO26894; AAO26894; bbp_161.
DR   GeneID; 1058129; -.
DR   KEGG; bab:bbp161; -.
DR   PATRIC; 21245099; VBIBucAph80364_0156.
DR   eggNOG; COG0216; -.
DR   KO; K02835; -.
DR   OMA; MANAKSK; -.
DR   OrthoDB; EOG6TN48J; -.
DR   ProtClustDB; PRK00591; -.
DR   BioCyc; BAPH224915:GJ9D-161-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016149; F:translation release factor activity, codon specific; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.30.160.20; -; 1.
DR   HAMAP; MF_00093; Rel_fac_1; 1.
DR   InterPro; IPR014720; dsRNA-bd_dom.
DR   InterPro; IPR005139; PCRF.
DR   InterPro; IPR000352; Pep_chain_release_fac_I_II.
DR   InterPro; IPR004373; PrfA.
DR   Pfam; PF03462; PCRF; 1.
DR   Pfam; PF00472; RF-1; 1.
DR   SMART; SM00937; PCRF; 1.
DR   TIGRFAMs; TIGR00019; prfA; 1.
DR   PROSITE; PS00745; RF_PROK_I; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methylation; Protein biosynthesis.
FT   CHAIN         1    362       Peptide chain release factor 1.
FT                                /FTId=PRO_0000177648.
FT   MOD_RES     235    235       N5-methylglutamine (By similarity).
SQ   SEQUENCE   362 AA;  41467 MW;  8D6C3CC0B676A45D CRC64;
     MKSSMMKKLE SLHRRYEEIE SMLSDRTVIS NQEKFRELSQ EYLKLSDINY CFVQWKNCNH
     DVIETKLLLL DSELHDVAEQ ELQMLSKKMK KIETEIQVLL LPCDPNDQQN CFLEIRSASG
     GDEAAIFSGD LFRMYIKYSE FQNWKTNIIH MTHSLKGGYK DIIVKITGKG SYGKLKFESG
     GHRVQRVPKT ESQGRVHTST CIVAVIPVVP KKEIEKVNIN DLKIDTFRSS GAGGQHVNTT
     DSAVRITHIP SGQVVECQDE RSQHKNKAKA LSVLVSRIKA AELYNQRKKN AIQRRDLLGT
     GMRSDRNRTY NFAQNRVTDH RINLVVYCLD EVLDGKLDVL IEPIIQEHNA DVLSNLSNIE
     FL
//