ID CBPX2_SULSO STANDARD; PRT; 393 AA. AC P58156; DT 16-OCT-2001 (Rel. 40, Created) DT 16-OCT-2001 (Rel. 40, Last sequence update) DT 01-FEB-2005 (Rel. 46, Last annotation update) DE Thermostable carboxypeptidase 2 (EC 3.4.17.-). GN Name=cpsA2; Synonyms=cpsA-2; OrderedLocusNames=SSO1952; OS Sulfolobus solfataricus. OC Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; OC Sulfolobus. OX NCBI_TaxID=2287; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 35092 / DSM 1617 / P2; RX MEDLINE=21332296; PubMed=11427726; DOI=10.1073/pnas.141222098; RA She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., RA Awayez M.J., Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., RA De Moors A., Erauso G., Fletcher C., Gordon P.M.K., RA Heikamp-de Jong I., Jeffries A.C., Kozera C.J., Medina N., Peng X., RA Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C., Tolstrup N., RA Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T., RA Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.; RT "The complete genome of the crenarchaeon Sulfolobus solfataricus P2."; RL Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001). CC -!- FUNCTION: Can release basic, acidic, aromatic, and, to a lesser CC extent, aliphatic amino acids (By similarity). CC -!- COFACTOR: Requires zinc (By similarity). CC -!- SUBUNIT: Homotetramer (By similarity). CC -!- SIMILARITY: Belongs to the peptidase M40 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE006803; AAK42144.1; -. DR PIR; A99361; A99361. DR InterPro; IPR010168; Pept_M20D_amidh. DR InterPro; IPR002933; Peptidase_M20. DR Pfam; PF01546; Peptidase_M20; 1. DR TIGRFAMs; TIGR01891; amidohydrolases; 1. KW Carboxypeptidase; Complete proteome; Hydrolase; Metalloprotease; Zinc. FT METAL 104 104 Zinc (Potential). FT METAL 109 109 Zinc (Potential). FT METAL 245 245 Zinc (Potential). FT ACT_SITE 302 302 Proton donor (Potential). FT ACT_SITE 373 373 Nucleophile (Potential). SQ SEQUENCE 393 AA; 42993 MW; AFBDE9F0A3469B63 CRC64; MDLVEKLKND VKEIEDWIIQ IRRKIHENPE LSYKEYSTSK LVAETLRKLG IEVEEGVGLP TAVVGKIRGN KPGKTVALRA DMDALPVEET SDVEFKSKVK GVMHACGHDT HVAMLLGGAY LLVKNKDLIS GEIRLIFQPA EEDGGLGGAK PMIEAGVMNG VDYVFGIHIS SSYPSGVFAT RKGPIMATPD AFKIVVHGKG GHGSAPHETI DPIFISLQIA NAIYGITARQ IDPVQPFVIS ITTIHSGTKD NIIPDDAEMQ GTIRSLDENV RSKAKDYMRR IVSSICGIYG ATCEVKFMED VYPITVNNPE VTDEVMKILS SISTVVETEP VLGAEDFSRF LQKAPGMYFF LGTRNEKKGC IYPNHSSKFC VDEDVLKLGA LAHALLAIKF SNK //