ID KPTA_THEAC Reviewed; 235 AA. AC P57718; Q9HLV7; DT 11-JAN-2001, integrated into UniProtKB/Swiss-Prot. DT 30-APR-2003, sequence version 2. DT 07-OCT-2020, entry version 90. DE RecName: Full=Probable RNA 2'-phosphotransferase; DE EC=2.7.1.-; GN Name=kptA; OrderedLocusNames=Ta0118; OS Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC OS 15155 / AMRC-C165). OC Archaea; Euryarchaeota; Diaforarchaea group; Thermoplasmata; OC Thermoplasmatales; Thermoplasmataceae; Thermoplasma. OX NCBI_TaxID=273075; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165; RX PubMed=11029001; DOI=10.1038/35035069; RA Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., RA Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.; RT "The genome sequence of the thermoacidophilic scavenger Thermoplasma RT acidophilum."; RL Nature 407:508-513(2000). CC -!- FUNCTION: Removes the 2'-phosphate from RNA via an intermediate in CC which the phosphate is ADP-ribosylated by NAD followed by a presumed CC transesterification to release the RNA and generate ADP-ribose 1''-2''- CC cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By CC similarity). {ECO:0000250}. CC -!- SIMILARITY: Belongs to the KptA/TPT1 family. {ECO:0000305}. CC -!- SEQUENCE CAUTION: CC Sequence=CAC11265.1; Type=Erroneous initiation; Evidence={ECO:0000305}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL445063; CAC11265.1; ALT_INIT; Genomic_DNA. DR RefSeq; WP_010900545.1; NC_002578.1. DR SMR; P57718; -. DR STRING; 273075.Ta0118m; -. DR PRIDE; P57718; -. DR EnsemblBacteria; CAC11265; CAC11265; CAC11265. DR GeneID; 1456972; -. DR KEGG; tac:Ta0118; -. DR eggNOG; arCOG04063; Archaea. DR HOGENOM; CLU_052998_4_1_2; -. DR KO; K07559; -. DR OMA; EHGYFRG; -. DR OrthoDB; 74155at2157; -. DR BioCyc; TACI273075:G1GT7-122-MONOMER; -. DR Proteomes; UP000001024; Chromosome. DR GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro. DR GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:UniProtKB-UniRule. DR GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:UniProtKB-UniRule. DR Gene3D; 1.10.10.970; -; 1. DR Gene3D; 3.20.170.30; -; 1. DR HAMAP; MF_00299; KptA; 1. DR InterPro; IPR002745; Ptrans_KptA/Tpt1. DR InterPro; IPR042081; RNA_2'-PTrans_C. DR InterPro; IPR022928; RNA_2'-PTrans_KptA. DR InterPro; IPR042080; RNA_2'-PTrans_N. DR PANTHER; PTHR12684; PTHR12684; 1. DR Pfam; PF01885; PTS_2-RNA; 1. PE 3: Inferred from homology; KW NAD; Reference proteome; Transferase. FT CHAIN 1..235 FT /note="Probable RNA 2'-phosphotransferase" FT /id="PRO_0000157495" SQ SEQUENCE 235 AA; 27050 MW; 70A4062661D63253 CRC64; MPELRTCHGP YRGRECPVCG KPGKILMNER EVDEVSRTLA AILRHDPERY HIRLDSHGYA RIAGIVTVLR KYKGMKWITF DHILSLAETD PKGRYQVSGV LIRAMYGHTI PVDLSDLPED NIPDVLYYQS SAAEAPLVKE AGIYPSDKTW VHLSGTYRRS YVSGLYHIDD PFILRIDARS MIDSGHDIYR SSDDIYLTRE IPPEYIQDAE PEEVTLTEEE KMDIDRVRNK NKKDQ //