ID KPTA_THEAC Reviewed; 235 AA. AC P57718; Q9HLV7; DT 11-JAN-2001, integrated into UniProtKB/Swiss-Prot. DT 30-APR-2003, sequence version 2. DT 10-AUG-2010, entry version 50. DE RecName: Full=Probable RNA 2'-phosphotransferase; DE EC=2.7.1.-; GN Name=kptA; OrderedLocusNames=Ta0118; OS Thermoplasma acidophilum. OC Archaea; Euryarchaeota; Thermoplasmata; Thermoplasmatales; OC Thermoplasmataceae; Thermoplasma. OX NCBI_TaxID=2303; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 25905 / AMRC-C165 / DSM 1728 / IFO 15155 / JCM 9062; RX MEDLINE=20479972; PubMed=11029001; DOI=10.1038/35035069; RA Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., RA Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.; RT "The genome sequence of the thermoacidophilic scavenger Thermoplasma RT acidophilum."; RL Nature 407:508-513(2000). CC -!- FUNCTION: Removes the 2'-phosphate from RNA via an intermediate in CC which the phosphate is ADP-ribosylated by NAD followed by a CC presumed transesterification to release the RNA and generate ADP- CC ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP- CC ribosylase (By similarity). CC -!- SIMILARITY: Belongs to the kptA/TPT1 family. CC -!- SEQUENCE CAUTION: CC Sequence=CAC11265.1; Type=Erroneous initiation; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL445063; CAC11265.1; ALT_INIT; Genomic_DNA. DR RefSeq; NP_393596.1; -. DR ProteinModelPortal; P57718; -. DR SMR; P57718; 34-214. DR GeneID; 1456972; -. DR GenomeReviews; AL139299_GR; Ta0118. DR NMPDR; fig|273075.1.peg.118; -. DR HOGENOM; HBG332834; -. DR OMA; GALRHFP; -. DR ProtClustDB; CLSK337093; -. DR BioCyc; TACI273075:TA0118-MONOMER; -. DR GO; GO:0016772; F:transferase activity, transferring phosphor...; IEA:InterPro. DR GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage...; IEA:InterPro. DR HAMAP; MF_00299; KptA; 1; -. DR InterPro; IPR002745; Ptrans_KptA/Tpt1. DR Pfam; PF01885; PTS_2-RNA; 1. PE 3: Inferred from homology; KW Complete proteome; NAD; Transferase. FT CHAIN 1 235 Probable RNA 2'-phosphotransferase. FT /FTId=PRO_0000157495. SQ SEQUENCE 235 AA; 27050 MW; 70A4062661D63253 CRC64; MPELRTCHGP YRGRECPVCG KPGKILMNER EVDEVSRTLA AILRHDPERY HIRLDSHGYA RIAGIVTVLR KYKGMKWITF DHILSLAETD PKGRYQVSGV LIRAMYGHTI PVDLSDLPED NIPDVLYYQS SAAEAPLVKE AGIYPSDKTW VHLSGTYRRS YVSGLYHIDD PFILRIDARS MIDSGHDIYR SSDDIYLTRE IPPEYIQDAE PEEVTLTEEE KMDIDRVRNK NKKDQ //