ID KPTA_THEAC STANDARD; PRT; 235 AA. AC P57718; Q9HLV7; DT 11-JAN-2001, integrated into UniProtKB/Swiss-Prot. DT 30-APR-2003, sequence version 2. DT 11-JUL-2006, entry version 26. DE Probable RNA 2'-phosphotransferase (EC 2.7.-.-). GN Name=kptA; OrderedLocusNames=Ta0118; OS Thermoplasma acidophilum. OC Archaea; Euryarchaeota; Thermoplasmata; Thermoplasmatales; OC Thermoplasmataceae; Thermoplasma. OX NCBI_TaxID=2303; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 25905 / AMRC-C165 / DSM 1728 / IFO 15155 / JCM 9062; RX MEDLINE=20479972; PubMed=11029001; DOI=10.1038/35035069; RA Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C., RA Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.; RT "The genome sequence of the thermoacidophilic scavenger Thermoplasma RT acidophilum."; RL Nature 407:508-513(2000). CC -!- FUNCTION: Removes the 2'-phosphate from RNA via an intermediate in CC which the phosphate is ADP-ribosylated by NAD followed by a CC presumed transesterification to release the RNA and generate ADP- CC ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP- CC ribosylase (By similarity). CC -!- SIMILARITY: Belongs to the kptA/TPT1 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL445063; CAC11265.1; ALT_INIT; Genomic_DNA. DR GenomeReviews; AL139299_GR; Ta0118. DR BioCyc; TACI2303:TA0118-MONOMER; -. DR HAMAP; MF_00299; -; 1. DR InterPro; IPR002745; Ptrans_KptA/Tpt1. DR Pfam; PF01885; PTS_2-RNA; 1. DR ProDom; PD009619; Ptrans_KptA/Tpt1; 1. KW Complete proteome; NAD; Transferase. FT CHAIN 1 235 Probable RNA 2'-phosphotransferase. FT /FTId=PRO_0000157495. SQ SEQUENCE 235 AA; 27050 MW; 70A4062661D63253 CRC64; MPELRTCHGP YRGRECPVCG KPGKILMNER EVDEVSRTLA AILRHDPERY HIRLDSHGYA RIAGIVTVLR KYKGMKWITF DHILSLAETD PKGRYQVSGV LIRAMYGHTI PVDLSDLPED NIPDVLYYQS SAAEAPLVKE AGIYPSDKTW VHLSGTYRRS YVSGLYHIDD PFILRIDARS MIDSGHDIYR SSDDIYLTRE IPPEYIQDAE PEEVTLTEEE KMDIDRVRNK NKKDQ //