ID XGPT_BUCAI STANDARD; PRT; 158 AA. AC P57339; DT 16-OCT-2001 (Rel. 40, Created) DT 16-OCT-2001 (Rel. 40, Last sequence update) DT 15-JUN-2002 (Rel. 41, Last annotation update) DE Xanthine-guanine phosphoribosyltransferase (EC 2.4.2.22) (XGPRT). GN GPT OR BU251. OS Buchnera aphidicola (subsp. Acyrthosiphon pisum) (Acyrthosiphon pisum OS symbiotic bacterium). OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Buchnera. OX NCBI_TaxID=118099; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=Tokyo 1998; RX MEDLINE=20445173; PubMed=10993077; RA Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.; RT "Genome sequence of the endocellular bacterial symbiont of aphids RT Buchnera sp. APS."; RL Nature 407:81-86(2000). CC -!- FUNCTION: ACTS ON GUANINE, XANTHINE AND TO A LESSER EXTENT CC HYPOXANTHINE (BY SIMILARITY). CC -!- CATALYTIC ACTIVITY: 5-phospho-alpha-D-ribose 1-diphosphate + CC xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate. CC -!- PATHWAY: Purine salvage. CC -!- SUBUNIT: Homotrimer (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasmic (By similarity). CC -!- SIMILARITY: BELONGS TO THE PURINE/PYRIMIDINE CC PHOSPHORIBOSYLTRANSFERASE FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AP001118; BAB12961.1; ALT_INIT. DR HSSP; P00501; 1A98. DR InterPro; IPR000836; PRTransferase. DR InterPro; IPR002375; Pr/py_rp_transf. DR Pfam; PF00156; Pribosyltran; 1. DR PROSITE; PS00103; PUR_PYR_PR_TRANSFER; 1. KW Transferase; Glycosyltransferase; Purine salvage; Complete proteome. SQ SEQUENCE 158 AA; 18064 MW; 2B40B2A98EAABF28 CRC64; MSEKYIVTWD MLQIHTRKLA NRLVKKIHSW NGIIAVSRGG LVPSALLARE LGLRCVDTVC IESYNYDCLK ENRKIIKKAE GNGEKIIVID DLVDTGGTAK IIRKLYPKAC FVTIFAKPMG RSLVDNYIID IPQNVWIEQP WDMSISYIPP LIQNYKIK //