ID GBB1_RAT STANDARD; PRT; 340 AA. AC P54311; DT 01-OCT-1996 (Rel. 34, Created) DT 01-OCT-1996 (Rel. 34, Last sequence update) DT 15-JUL-1998 (Rel. 36, Last annotation update) DE GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(T) BETA SUBUNIT 1 DE (TRANSDUCIN BETA CHAIN 1). GN GNB1. OS Rattus norvegicus (Rat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Rattus. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=SPRAGUE-DAWLEY; TISSUE=BRAIN; RA Kuroda S., Tokunaga C., Konishi H., Kikkawa U.; RL Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: GUANINE NUCLEOTIDE-BINDING PROTEINS (G PROTEINS) ARE CC INVOLVED AS A MODULATOR OR TRANSDUCER IN VARIOUS TRANSMEMBRANE CC SIGNALING SYSTEMS. THE BETA AND GAMMA CHAINS ARE REQUIRED FOR THE CC GTPASE ACTIVITY, FOR REPLACEMENT OF GDP BY GTP, AND FOR G PROTEIN- CC EFFECTOR INTERACTION. CC -!- SUBUNIT: G PROTEINS ARE COMPOSED OF 3 UNITS (ALPHA, BETA & GAMMA). CC -!- SIMILARITY: CONTAINS 7 WD REPEATS (TRP-ASP DOMAINS). CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U34958; AAC72249.1; -. DR HSSP; P04901; 1TBG. DR INTERPRO; IPR001632; -. DR INTERPRO; IPR001680; -. DR PFAM; PF00400; WD40; 7. DR PRINTS; PR00319; GPROTEINB. DR PRINTS; PR00320; GPROTEINBRPT. DR PROSITE; PS00678; WD_REPEATS; 3. KW Transducer; Repeat; WD repeat; Multigene family. FT REPEAT 53 83 WD1. FT REPEAT 95 125 WD2. FT REPEAT 141 170 WD3. FT REPEAT 182 212 WD4. FT REPEAT 224 254 WD5. FT REPEAT 268 298 WD6. FT REPEAT 310 340 WD7. SQ SEQUENCE 340 AA; 37393 MW; 89755AACB2686598 CRC64; MSELDQLRQE AEQLKNQIRD ARKACADATL SQITNNIDPV GRIQMRTRRT LRGHLAKIYA MHWGTDSRLL VSASQDGKLI IWDSYTTNKV HAIPLRSSWV MTCAYAPSGN YVACGGLDNI CSIYNLKTRE GNVRVSRELA GHTGYLSCCR FLDDNQIVTS SGDTTCALWD IETGQQTTTF TGHTGDVMSL SLAPDTRLFV SGACDASAKL WDVREGMCRQ TFTGHESDIN AICFFPNGNA FATGSDDATC RLFDLRADQE LMTYSHDNII CGITSVSFSK SGRLLLAGYD DFNCNVWDAL KADRAGDLAG HDNRVSCLGV TDDGMAVATG SWDSFLKIWN //