ID   PHZR_PSECL              Reviewed;         241 AA.
AC   P54303;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   01-OCT-2014, entry version 69.
DE   RecName: Full=Transcriptional activator protein PhzR;
GN   Name=phzR;
OS   Pseudomonas chlororaphis (Pseudomonas aureofaciens).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=30-84;
RX   PubMed=8021179;
RA   Pierson L.S. III, Keppenne V.D., Wood D.W.;
RT   "Phenazine antibiotic biosynthesis in Pseudomonas aureofaciens 30-84
RT   is regulated by PhzR in response to cell density.";
RL   J. Bacteriol. 176:3966-3974(1994).
CC   -!- FUNCTION: Positive regulator of phenazine antibiotic production.
CC       May activate the phenazine biosynthetic genes by binding to a DNA
CC       sequence upstream of them, or to an intermediate gene which, in
CC       turn, interacts with them.
CC   -!- SIMILARITY: Belongs to the autoinducer-regulated transcriptional
CC       regulatory protein family. {ECO:0000305}.
CC   -!- SIMILARITY: Contains 1 HTH luxR-type DNA-binding domain.
CC       {ECO:0000255|PROSITE-ProRule:PRU00411}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L32729; AAA21841.1; -; Genomic_DNA.
DR   ProteinModelPortal; P54303; -.
DR   PRIDE; P54303; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.450.80; -; 1.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR005143; TF_LuxR_autoind-bd_dom.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   Pfam; PF03472; Autoind_bind; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF75516; SSF75516; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   3: Inferred from homology;
KW   Activator; Antibiotic biosynthesis; DNA-binding; Quorum sensing;
KW   Transcription; Transcription regulation.
FT   CHAIN         1    241       Transcriptional activator protein PhzR.
FT                                /FTId=PRO_0000184175.
FT   DOMAIN      174    239       HTH luxR-type. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00411}.
FT   DNA_BIND    198    217       H-T-H motif. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00411}.
SQ   SEQUENCE   241 AA;  27426 MW;  39DBE6AF00FFBCB2 CRC64;
     MELGQQLGWD AYFYSIFART MDMQEFTAVA LRALRELRFD FFRYGMCSVT PFMRPRTYMY
     GNYPEDWVQR YQAANYAVID PTVKHSKVSS SPILASNELF RGCPDLWSEA NDSNLRHGLA
     QPSFNTQGRV GVLSLARKDN PISLQEFEAL KVVTKAFAAA VHEKISELES DVRVFNTDVE
     FSGRECDVLR WTADGKTSEE IGVIMGVCTD TVNYHHRNIQ RKIGASNRVQ ASRYAVAMGY
     I
//