ID   PHZR_PSECL              Reviewed;         241 AA.
AC   P54303;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   12-JUN-2007, entry version 38.
DE   Transcriptional activator protein phzR.
GN   Name=phzR;
OS   Pseudomonas chlororaphis (Pseudomonas aureofaciens).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=30-84;
RX   MEDLINE=94292415; PubMed=8021179;
RA   Pierson L.S. III, Keppenne V.D., Wood D.W.;
RT   "Phenazine antibiotic biosynthesis in Pseudomonas aureofaciens 30-84
RT   is regulated by PhzR in response to cell density.";
RL   J. Bacteriol. 176:3966-3974(1994).
CC   -!- FUNCTION: Positive regulator of phenazine antibiotic production.
CC       May activate the phenazine biosynthetic genes by binding to a DNA
CC       sequence upstream of them, or to an intermediate gene which, in
CC       turn, interacts with them.
CC   -!- SIMILARITY: Belongs to the autoinducer-regulated transcriptional
CC       regulatory protein family.
CC   -!- SIMILARITY: Contains 1 HTH luxR-type DNA-binding domain.
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DR   EMBL; L32729; AAA21841.1; -; Genomic_DNA.
DR   InterPro; IPR005143; Autoind_bd.
DR   InterPro; IPR000792; HTH_LuxR.
DR   InterPro; IPR011991; Wing_hlx_DNA_bd.
DR   Gene3D; G3DSA:1.10.10.10; Wing_hlx_DNA_bd; 1.
DR   Pfam; PF03472; Autoind_bind; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   ProDom; PD000307; HTH_LuxR; 1.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
KW   Activator; Antibiotic biosynthesis; DNA-binding; Quorum sensing;
KW   Transcription; Transcription regulation.
FT   CHAIN         1    241       Transcriptional activator protein phzR.
FT                                /FTId=PRO_0000184175.
FT   DOMAIN      174    239       HTH luxR-type.
FT   DNA_BIND    198    217       H-T-H motif (By similarity).
SQ   SEQUENCE   241 AA;  27426 MW;  39DBE6AF00FFBCB2 CRC64;
     MELGQQLGWD AYFYSIFART MDMQEFTAVA LRALRELRFD FFRYGMCSVT PFMRPRTYMY
     GNYPEDWVQR YQAANYAVID PTVKHSKVSS SPILASNELF RGCPDLWSEA NDSNLRHGLA
     QPSFNTQGRV GVLSLARKDN PISLQEFEAL KVVTKAFAAA VHEKISELES DVRVFNTDVE
     FSGRECDVLR WTADGKTSEE IGVIMGVCTD TVNYHHRNIQ RKIGASNRVQ ASRYAVAMGY
     I
//