ID ASI2_YEAST Reviewed; 289 AA. AC P53895; DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot. DT 01-OCT-1996, sequence version 1. DT 18-MAR-2008, entry version 46. DE Protein ASI2 (Amino acid sensor-independent protein 2). GN Name=ASI2; OrderedLocusNames=YNL159C; ORFNames=N1735; OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 96604 / S288c / FY1679; RX MEDLINE=96287653; PubMed=8686380; RX DOI=10.1002/(SICI)1097-0061(199602)12:2<169::AID-YEA894>3.0.CO;2-B; RA Nasr F., Becam A.-M., Herbert C.J.; RT "The sequence of 36.8 kb from the left arm of chromosome XIV reveals RT 24 complete open reading frames: 18 correspond to new genes, one of RT which encodes a protein similar to the human myotonic dystrophy RT kinase."; RL Yeast 12:169-175(1996). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 96604 / S288c / FY1679; RX MEDLINE=97313269; PubMed=9169873; RA Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., RA Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., RA Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., RA Beinhauer J.D., Boskovic J., Buitrago M.J., Bussereau F., Coster F., RA Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., RA Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., RA Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., RA Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., RA Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., RA Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., RA Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., RA Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., RA Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., RA Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., RA Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., RA Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., RA Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., RA Wambutt R., Wedler H., Zollner A., Hani J.; RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV RT and its evolutionary implications."; RL Nature 387:93-98(1997). RN [3] RP TOPOLOGY [LARGE SCALE ANALYSIS]. RX PubMed=16847258; DOI=10.1073/pnas.0604075103; RA Kim H., Melen K., Oesterberg M., von Heijne G.; RT "A global topology map of the Saccharomyces cerevisiae membrane RT proteome."; RL Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006). CC -!- INTERACTION: CC Self; NbExp=1; IntAct=EBI-28975, EBI-28975; CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X92517; CAA63280.1; -; Genomic_DNA. DR EMBL; Z71435; CAA96046.1; -; Genomic_DNA. DR PIR; S60968; S60968. DR RefSeq; NP_014240.1; -. DR DIP; DIP:4337N; -. DR IntAct; P53895; -. DR Ensembl; YNL159C; Saccharomyces cerevisiae. DR GeneID; 855563; -. DR GenomeReviews; Y13139_GR; YNL159C. DR KEGG; sce:YNL159C; -. DR CYGD; YNL159c; -. DR SGD; S000005103; ASI2. DR LinkHub; P53895; -. DR ArrayExpress; P53895; -. DR GermOnline; YNL159C; Saccharomyces cerevisiae. DR GO; GO:0005637; C:nuclear inner membrane; IDA:SGD. DR GO; GO:0042802; F:identical protein binding; IPI:IntAct. DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IGI:SGD. PE 1: Evidence at protein level; KW Complete proteome; Membrane; Transmembrane. FT CHAIN 1 289 Protein ASI2. FT /FTId=PRO_0000203414. FT TOPO_DOM 1 121 Cytoplasmic (Potential). FT TRANSMEM 122 142 Potential. FT TOPO_DOM 143 247 Extracellular (Potential). FT TRANSMEM 248 268 Potential. FT TOPO_DOM 269 289 Cytoplasmic (Potential). SQ SEQUENCE 289 AA; 32986 MW; 95C425488F1E3724 CRC64; MARPQNHRRS NWTERDDNDD YLFQRFLEES ETRHSREPSP VTEQSQQELQ QDVQQAIDGI FNSLRRNMSS TSNINRAANM DATTNGNGGI NADTIRATNA NTADSPFTAR QQSPLRTFLR NLFILDYFIG LILFPFSVYN ILRSGFNSMT FSENDFIIEI VGYWKFAKIF GSGGTTLIAY KDTGKLGLLG KFHNIIVFYS SPVIKHIMKS RDGNEPNLNW IRLMFAKAFE LFVKVSTILI YLAYGVSGTV YMVTAGFFFV LCLLFTVIRR YKGVHRMLVS QRITGPGVF //