ID ACT3_DROME STANDARD; PRT; 376 AA. AC P53501; DT 01-OCT-1996 (REL. 34, CREATED) DT 01-OCT-1996 (REL. 34, LAST SEQUENCE UPDATE) DT 01-OCT-1996 (REL. 34, LAST ANNOTATION UPDATE) DE ACTIN 57A. GN ACT57A. OS DROSOPHILA MELANOGASTER (FRUIT FLY). OC EUKARYOTA; METAZOA; ARTHROPODA; INSECTA; DIPTERA. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 81210174. RA FYRBERG E.A., BOND B.J., HERSHEY N.D., MIXTER K.S., DAVIDSON N.; RL CELL 24:107-116(1981). RN [2] RP SEQUENCE FROM N.A. RA FYRBERG E.A., BOND B.J., HERSHEY N.D., MIXTER K.S., DAVIDSON N.; RL SUBMITTED (JUN-1985) TO EMBL/GENBANK/DDBJ DATA BANKS. CC -!- FUNCTION: ACTINS ARE HIGHLY CONSERVED PROTEINS THAT ARE INVOLVED CC IN VARIOUS TYPES OF CELL MOTILITY AND ARE UBIQUITOUSLY EXPRESSED CC IN ALL EUKARYOTIC CELLS. CC -!- FUNCTION: MULTIPLE ISOFORMS ARE INVOLVED IN VARIOUS CELLULAR CC FUNCTIONS SUCH AS CYTOSKELETON STRUCTURE, CELL MOBILITY, CC CHROMOSOME MOVEMENT AND MUSCLE CONTRACTION. CC -!- SUBCELLULAR LOCATION: CYTOPLASMIC. CC -!- IN DROSOPHILA THERE ARE 6 CLOSELY RELATED ACTIN GENES. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; K00673; G156769; -. DR EMBL; K00672; G156769; JOINED. DR FLYBASE; FBGN0000044; ACT57A. KW STRUCTURAL PROTEIN; MULTIGENE FAMILY; ACETYLATION. FT PROPEP 1 2 REMOVED IN MATURE FORM (BY SIMILARITY). FT CHAIN 3 376 ACTIN-57A. FT MOD_RES 3 3 ACETYLATION (BY SIMILARITY). SQ SEQUENCE 376 AA; 41835 MW; 8E5702FB CRC32; MCDDEVAALV VDNGSGMCKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ SKRGILTLKY PIEHGIITNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM TQIMFETFNS PAMYVAIQAV LSLYASGRTT GIVLDSGDGV SHTVPIYEGY ALPHAILRLD LAGRDLTDYL MKILTERGYS FTTTAEREIV RDIKEKLCYV ALDFEQEMAT AAASTSLEKS YELPDGQVIT IGNERFRCPE SLFQPSFLGM ESCGIHETVY NSIMKCDVDI RKDLYANIVM SGGTTMYPGI ADRMQKEITS LAPSTIKIKI IAPPERKYSV WIGGSILASL STFQQMWISK EEYDESGPGI VHRKCF //