ID UFD1_YEAST STANDARD; PRT; 361 AA. AC P53044; DT 01-OCT-1996 (Rel. 34, Created) DT 01-OCT-1996 (Rel. 34, Last sequence update) DT 16-OCT-2001 (Rel. 40, Last annotation update) DE Ubiquitin fusion degradation protein 1 (UB fusion protein 1) DE (Polymerase-interacting protein 3). GN UFD1 OR PIP3 OR YGR048W. OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=S288c; RX MEDLINE=95340540; PubMed=7615550; RA Johnson E.S., Ma P.C.M., Ota I.M., Varshavsky A.; RT "A proteolytic pathway that recognizes ubiquitin as a degradation RT signal."; RL J. Biol. Chem. 270:17442-17456(1995). RN [2] RP SEQUENCE FROM N.A. RA Entian K.D., Rose M., Koetter P., Roehmer A., Sehrsam I., Hempel S.; RL Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases. RN [3] RP SEQUENCE FROM N.A. RC STRAIN=W303; RX MEDLINE=97379980; PubMed=9236779; RA del Olmo M., Mizrahi N., Gross S., Moore C.L.; RT "The Uba2 and Ufd1 proteins of Saccharomyces cerevisiae interact with RT poly(A) polymerase and affect the polyadenylation activity of cell RT extracts."; RL Mol. Gen. Genet. 255:209-218(1997). CC -!- FUNCTION: FUNCTIONS AT A POST-UBIQUITATION STEP IN THE UBIQUITIN CC FUSION DEGRADATION (UFD) PATHWAY. IT IS REQUIRED FOR VEGETATIVE CC GROWTH. CC -!- SIMILARITY: BELONGS TO THE UFD1 FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U22153; AAC49023.1; -. DR EMBL; Z72833; CAA97047.1; -. DR EMBL; U17264; AAB46627.1; -. DR SGD; S0003280; UFD1. DR InterPro; IPR004854; UFD1. DR Pfam; PF03152; UFD1; 1. KW Ubl conjugation pathway. FT VARIANT 94 94 V -> D (IN UFD1-1; GROWS MORE SLOWLY). SQ SEQUENCE 361 AA; 39810 MW; 198E0CD48B863B98 CRC64; MFSGFSSFGG GNGFVNMPQT FEEFFRCYPI AMMNDRIRKD DANFGGKIFL PPSALSKLSM LNIRYPMLFK LTANETGRVT HGGVLEFIAE EGRVYLPQWM METLGIQPGS LLQISSTDVP LGQFVKLEPQ SVDFLDISDP KAVLENVLRN FSTLTVDDVI EISYNGKTFK IKILEVKPES SSKSICVIET DLVTDFAPPV GYVEPDYKAL KAQQDKEKKN SFGKGQVLDP SVLGQGSMST RIDYAGIANS SRNKLSKFVG QGQNISGKAP KAEPKQDIKD MKITFDGEPA KLDLPEGQLF FGFPMVLPKE DEESAAGSKS SEQNFQGQGI SLRKSNKRKT KSDHDSSKSK APKSPEVIEI D //