ID YFHK_ECOLI STANDARD; PRT; 496 AA. AC P52101; P76587; DT 01-OCT-1996 (Rel. 34, Created) DT 01-NOV-1997 (Rel. 35, Last sequence update) DT 01-NOV-1997 (Rel. 35, Last annotation update) DE PROBABLE SENSOR PROTEIN YFHK (EC 2.7.3.-). GN YFHK. OS Escherichia coli. OC Bacteria; Proteobacteria; gamma subdivision; Enterobacteriaceae; OC Escherichia. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=K12 / MG1655; RX MEDLINE; 97426617. RA BLATTNER F.R., PLUNKETT G. III, BLOCH C.A., PERNA N.T., BURLAND V., RA RILEY M., COLLADO-VIDES J., GLASNER F.D., RODE C.K., MAYHEW G.F., RA GREGOR J., DAVIS N.W., KIRKPATRICK H.A., GOEDEN M.A., ROSE D.J., RA MAU B., SHAO Y.; RT "The complete genome sequence of Escherichia coli K-12."; RL Science 277:1453-1474(1997). CC -!- FUNCTION: PROBABLE MEMBER OF A TWO-COMPONENT REGULATORY SYSTEM CC YFHK/YFHA. MAY ACTIVATES YFHA BY PHOSPHORYLATION. CC -!- SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE CC (PROBABLE). CC -!- SIMILARITY: TO OTHER PROKARYOTIC SENSORY TRANSDUCTION HISTIDINE CC KINASES. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U36841; AAA79818.1; ALT_INIT. DR EMBL; AE000342; AAC75609.1; -. DR ECOGENE; EG13214; YFHK. DR PFAM; PF00512; signal; 1. DR PFAM; PF00672; DUF5; 1. KW Hypothetical protein; Sensory transduction; Transferase; Kinase; KW Transmembrane; Inner membrane; Phosphorylation. FT DOMAIN 1 34 CYTOPLASMIC (POTENTIAL). FT TRANSMEM 35 55 POTENTIAL. FT DOMAIN 56 194 PERIPLASMIC (POTENTIAL). FT TRANSMEM 195 215 POTENTIAL. FT DOMAIN 216 496 CYTOPLASMIC (POTENTIAL). FT MOD_RES 280 280 PHOSPHORYLATION (AUTO-) (BY SIMILARITY). SQ SEQUENCE 496 AA; 55699 MW; 75154CAE CRC32; MLYLNFPSVS IRLFASDESN TLKRWPVFPR SLRQLVMLAF LLILLPLLVL AWQAWQSLNA LSDQAALVNR TTLIDARRSE AMTNAALEME RSYRQYCVLD DPTLAKVYQS QRKRYSEMLD AHAGVLPDDK LYQALRQDLH NLAQLQCNNS GPDAAAAARL EAFASANTEM VQATRTVVFS RGQQLQREIA ERGQYFGWQS LVLFLVSLVM VLLFTRMIIG PVKNIERMIN RLGEGRSLGN SVSFSGPSEL RSVGQRILWL SERLSWLESQ RHQFLRHLSH ELKTPLASMR EGTELLADQV VGPLTPEQKE VVSILDSSSR NLQKLIEQLL DYNRKQADSA VELENVELAP LVETVVSAHS LPARAKMMHT DVDLKATACL AEPMLLMSVL DNLYSNAVHY GAESGNICLR SSLHGARVYI DVINTGTPIP QEERAMIFEP FFQGSHQRKG AVKGSGLGLS IARDCIRRMQ GELYLVDESG QDVCFRIELP SSKNTK //