ID   ERA_COXBU               Reviewed;         295 AA.
AC   P51836;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   10-JUL-2007, entry version 55.
DE   GTP-binding protein era homolog.
GN   Name=era; OrderedLocusNames=CBU_1502;
OS   Coxiella burnetii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Coxiellaceae; Coxiella.
OX   NCBI_TaxID=777;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CB9MIC7;
RX   MEDLINE=95131751; PubMed=7830573;
RA   Zuber M., Hoover T.A., Powell B.S., Court D.L.;
RT   "Analysis of the rnc locus of Coxiella burnetii.";
RL   Mol. Microbiol. 14:291-300(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nine Mile phase I / RSA 493;
RX   MEDLINE=22608657; PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA   Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E.,
RA   Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J.,
RA   DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J.,
RA   Khouri H.M., Lee K.H., Carty H.A., Scanlan D., Heinzen R.A.,
RA   Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F.;
RT   "Complete genome sequence of the Q-fever pathogen, Coxiella
RT   burnetii.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
CC   -!- FUNCTION: Binds both GDP and GTP, has an intrinsic GTPase activity
CC       and is essential for cell growth (By similarity).
CC   -!- SIMILARITY: Belongs to the era/trmE GTP-binding protein family.
CC       Era subfamily.
CC   -!- SIMILARITY: Contains 1 KH type-2 domain.
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DR   EMBL; L27436; AAA69691.1; -; Genomic_DNA.
DR   EMBL; AE016828; AAO90999.1; -; Genomic_DNA.
DR   PIR; S60768; S60768.
DR   HSSP; Q9X1F8; 1MKY.
DR   GenomeReviews; AE016828_GR; CBU_1502.
DR   KEGG; cbu:CBU_1502; -.
DR   TIGR; CBU_1502; -.
DR   BioCyc; CBUR227377:CBU_1502-MONOMER; -.
DR   GO; GO:0005525; F:GTP binding; IEA:HAMAP.
DR   GO; GO:0003723; F:RNA binding; IEA:HAMAP.
DR   GO; GO:0009987; P:cellular process; IEA:HAMAP.
DR   HAMAP; MF_00367; -; 1.
DR   InterPro; IPR005662; Era_GTP_bd.
DR   InterPro; IPR006073; GTP1_OBG.
DR   InterPro; IPR005289; GTP_bd.
DR   InterPro; IPR009019; KH_prok-type.
DR   InterPro; IPR004044; KH_type_2.
DR   InterPro; IPR002917; MMR_HSR1_GTP_bd.
DR   InterPro; IPR005225; Small_GTP_bd.
DR   Gene3D; G3DSA:3.30.300.20; KH_prok; 1.
DR   Pfam; PF07650; KH_2; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   TIGRFAMs; TIGR00436; era; 1.
DR   TIGRFAMs; TIGR00650; MG442; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS50823; KH_TYPE_2; 1.
KW   Complete proteome; GTP-binding; Nucleotide-binding; RNA-binding.
FT   CHAIN         1    295       GTP-binding protein era homolog.
FT                                /FTId=PRO_0000180010.
FT   DOMAIN      203    279       KH type-2.
FT   NP_BIND      13     20       GTP (Potential).
FT   NP_BIND      60     64       GTP (Potential).
FT   NP_BIND     121    124       GTP (Potential).
SQ   SEQUENCE   295 AA;  33873 MW;  559AB52D2922119E CRC64;
     MKPTYCGYAA IIGRPNVGKS TLLNQLLEQK ISITSRKPQT TRYQILGVKT FKDIQVIYVD
     TPGLHAGTER TINRYMNRTA RGALRDVDAI VFVIEPHWES QDAWVLDNLK EIETPVFLVI
     NKVDKIKNRA ELLPLIEKVS SLYAFQKITP LSAKTGDQVG TLEQAVHQLM PESPFYFPPE
     QVTDRSDQFM ASEIIREKLM RLLGQEIPYS LAVTLIEFRK EEKIIRISAV IWVEKKSQKG
     IVIGKGGERL KRVGTNARLD MEKWFGKRVF LQLWVKVKSG WADNERLLRE LGFEE
//