ID ERA_COXBU STANDARD; PRT; 295 AA. AC P51836; DT 01-OCT-1996 (Rel. 34, Created) DT 01-OCT-1996 (Rel. 34, Last sequence update) DT 01-FEB-2005 (Rel. 46, Last annotation update) DE GTP-binding protein era homolog. GN Name=era; OrderedLocusNames=CBU1502; OS Coxiella burnetii. OC Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; OC Coxiellaceae; Coxiella. OX NCBI_TaxID=777; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=CB9MIC7; RX MEDLINE=95131751; PubMed=7830573; RA Zuber M., Hoover T.A., Powell B.S., Court D.L.; RT "Analysis of the rnc locus of Coxiella burnetii."; RL Mol. Microbiol. 14:291-300(1994). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Nine Mile phase I / RSA 493; RX MEDLINE=22608657; PubMed=12704232; DOI=10.1073/pnas.0931379100; RA Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., RA Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., RA DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., RA Khouri H.M., Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., RA Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F.; RT "Complete genome sequence of the Q-fever pathogen, Coxiella RT burnetii."; RL Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003). CC -!- FUNCTION: Binds both GDP and GTP, has an intrinsic GTPase activity CC and is essential for cell growth (By similarity). CC -!- SIMILARITY: Belongs to the era/trmE GTP-binding protein family. CC Era subfamily. CC -!- SIMILARITY: Contains 1 KH type-2 domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L27436; AAA69691.1; -. DR EMBL; AE016964; AAO90999.1; -. DR PIR; S60768; S60768. DR HSSP; Q9X1F8; 1MKY. DR TIGR; CBU1502; -. DR HAMAP; MF_00367; -; 1. DR InterPro; IPR005662; Era. DR InterPro; IPR005289; GTP-binding. DR InterPro; IPR006073; GTP1_OBG. DR InterPro; IPR009019; KH_prok. DR InterPro; IPR004044; KH_TYPE_2. DR InterPro; IPR005225; Small_GTP. DR Pfam; PF00013; KH; 1. DR PRINTS; PR00326; GTP1OBG. DR TIGRFAMs; TIGR00436; era; 1. DR TIGRFAMs; TIGR00650; MG442; 1. DR TIGRFAMs; TIGR00231; small_GTP; 1. DR PROSITE; PS50823; KH_TYPE_2; 1. KW Complete proteome; GTP-binding; RNA-binding. FT NP_BIND 13 20 GTP (Potential). FT NP_BIND 60 64 GTP (Potential). FT NP_BIND 121 124 GTP (Potential). FT DOMAIN 203 279 KH type-2. SQ SEQUENCE 295 AA; 33873 MW; 559AB52D2922119E CRC64; MKPTYCGYAA IIGRPNVGKS TLLNQLLEQK ISITSRKPQT TRYQILGVKT FKDIQVIYVD TPGLHAGTER TINRYMNRTA RGALRDVDAI VFVIEPHWES QDAWVLDNLK EIETPVFLVI NKVDKIKNRA ELLPLIEKVS SLYAFQKITP LSAKTGDQVG TLEQAVHQLM PESPFYFPPE QVTDRSDQFM ASEIIREKLM RLLGQEIPYS LAVTLIEFRK EEKIIRISAV IWVEKKSQKG IVIGKGGERL KRVGTNARLD MEKWFGKRVF LQLWVKVKSG WADNERLLRE LGFEE //