ID DNAJ_FRATU STANDARD; PRT; 371 AA. AC P48207; DT 01-FEB-1996 (Rel. 33, Created) DT 01-FEB-1996 (Rel. 33, Last sequence update) DT 16-OCT-2001 (Rel. 40, Last annotation update) DE Chaperone protein dnaJ. GN DNAJ. OS Francisella tularensis. OC Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales; OC Francisellaceae; Francisella. OX NCBI_TaxID=263; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=96060855; PubMed=7590305; RA Zuber M., Hoover T.A., Dertzbaugh M.T., Court D.L.; RT "Analysis of the DnaK molecular chaperone system of Francisella RT tularensis."; RL Gene 164:149-152(1995). CC -!- FUNCTION: Acts as a co-chaperone. Stimulates, jointly with grpE, CC the ATPase activity of dnaK (By similarity). CC -!- COFACTOR: Binds 2 zinc ions per monomer (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasmic (By similarity). CC -!- SIMILARITY: Belongs to the dnaJ family. CC -!- SIMILARITY: Contains 1 CR domain. CC -!- SIMILARITY: Contains 1 J domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L43367; AAA69562.1; -. DR HSSP; P08622; 1BQZ. DR InterPro; IPR002939; DnaJ_C. DR InterPro; IPR001305; DnaJ_CXXCXGXG. DR InterPro; IPR001623; DnaJ_N. DR InterPro; IPR008971; HSP40_DnaJ_pep. DR InterPro; IPR003095; Hsp_DnaJ. DR Pfam; PF00226; DnaJ; 1. DR Pfam; PF01556; DnaJ_C; 1. DR Pfam; PF00684; DnaJ_CXXCXGXG; 1. DR PRINTS; PR00625; DNAJPROTEIN. DR SMART; SM00271; DnaJ; 1. DR PROSITE; PS00636; DNAJ_1; 1. DR PROSITE; PS50076; DNAJ_2; 1. DR PROSITE; PS00637; DNAJ_CXXCXGXG; 1. KW Chaperone; DNA replication; Heat shock; Repeat; Zinc; Metal-binding. FT DOMAIN 3 72 J-domain. FT DOMAIN 79 110 Gly-rich. FT REPEAT 140 147 CXXCXGXG motif. FT REPEAT 156 163 CXXCXGXG motif. FT REPEAT 178 185 CXXCXGXG motif. FT REPEAT 192 199 CXXCXGXG motif. FT METAL 140 140 Zinc 1 (By similarity). FT METAL 143 143 Zinc 1 (By similarity). FT METAL 156 156 Zinc 2 (By similarity). FT METAL 159 159 Zinc 2 (By similarity). FT METAL 178 178 Zinc 2 (By similarity). FT METAL 181 181 Zinc 2 (By similarity). FT METAL 192 192 Zinc 1 (By similarity). FT METAL 195 195 Zinc 1 (By similarity). SQ SEQUENCE 371 AA; 41481 MW; BBDC7F3B4741EF1E CRC64; MQQKCYYEIL NISKTASGVE IKRAYRKLAM KYHPDRNPGD KEAEIKFKEI SEAYEILSDD SKRSRYDQFG HAGVNQQSGF GGTGGFEDIF DTFFGGGTSR GSNRSRASRG SDLEYTLEIT LEEAFFGVEK EITIPRMESC DSCDGTGSKS RSKTTCHACH GQGTIRRQQG FFAFEQTCPV CNGTGYSITD PCDACYGNGK VKKQKTLKVK IPEGVDNGDR IRLQGEGDSG SNGAMNGDLY VQIIIKEHKI FERRDINLYC EMPISFTKAC LGGDIKVPTL DGEVVLKVVP ETQTGKVFRL REKGMKSLRG HRRGDLLCKV VVETPVNLSA EQKELLEKFA DSLGEDYQSK HAPKSKTWFD NVKDYAKKFF E //