ID TTP_RAT STANDARD; PRT; 320 AA. AC P47973; DT 01-OCT-1996 (REL. 34, CREATED) DT 01-OCT-1996 (REL. 34, LAST SEQUENCE UPDATE) DT 01-OCT-1996 (REL. 34, LAST ANNOTATION UPDATE) DE TRISTETRAPROLINE (TTP) (TIS11A) (TIS11) (ZFP-36). GN TIS11A. OS RATTUS NORVEGICUS (RAT). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA; OC EUTHERIA; RODENTIA. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 92380517. RA KANEDA N., OSHIMA M., CHUNG S.Y., GUROFF G.; RL GENE 118:289-291(1992). CC -!- FUNCTION: PROBABLE REGULATORY PROTEIN WITH A NOVEL ZINC FINGER CC STRUCTURE INVOLVED IN REGULATING THE RESPONSE TO GROWTH FACTORS. CC HAS BEEN EXPERIMENTALY SHOWN TO BE ABLE TO BIND ZINC. CC -!- SUBCELLULAR LOCATION: NUCLEAR. CC -!- SIMILARITY: CONTAINS 2 CX(8)CX(5)CX(3)H-TYPE ZINC FINGERS. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X63369; G57759; -. KW NUCLEAR PROTEIN; REPEAT; METAL-BINDING; ZINC-FINGER; DNA-BINDING; KW PHOSPHORYLATION. FT REPEAT 64 68 P-P-P-P-G. FT REPEAT 191 195 P-P-P-P-G. FT REPEAT 212 216 P-P-P-P-G. FT ZN_FING 102 121 CX(8)CX(5)CX(3)H-TYPE. FT ZN_FING 140 159 CX(8)CX(5)CX(3)H-TYPE. FT MOD_RES 221 221 PHOSPHORYLATION (BY MAPK) (BY FT SIMILARITY). SQ SEQUENCE 320 AA; 33653 MW; 62F12181 CRC32; MDLSAIYESL MSMSHDLSPD HGGTESSGGL WNINSSDSIP SGVTSRLTGR STSLVEGRSC SWVPPPPGFA PLAPRPGPEL SPSPTSPTAT PTTSSRYKTE LCRTYSESGR CRYGAKCQFA HGPGELRQAN RHPKYKTELC HKFYLQGRCP YGSRCHFIHN PTEDLALPGQ PHVLRQSISF SGLPSGRRTS PPPPGFSGPS LSSCSFSPSS SPPPPGDLPL SPSAFSAAPG TPVSRRDPTP ACCPSCRRST TPSTIWGPLG GLARSPSAHS LGSDPDDYAS SGSSLGGSDS PVFEAGVFGP PQPPAPPRRL PIFNRISVSE //