ID CDD_MYCGE STANDARD; PRT; 130 AA. AC P47298; DT 01-FEB-1996 (Rel. 33, Created) DT 01-FEB-1996 (Rel. 33, Last sequence update) DT 01-NOV-1997 (Rel. 35, Last annotation update) DE CYTIDINE DEAMINASE (EC 3.5.4.5) (CYTIDINE AMINOHYDROLASE) (CDA). GN CDD OR MG052. OS Mycoplasma genitalium. OC Bacteria; Firmicutes; Bacillus/Clostridium group; Mollicutes; OC Mycoplasmataceae; Mycoplasma. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=ATCC 33530 / G-37; RX MEDLINE; 96026346. RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G., Kelley J.M., RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M., RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.; RT "The minimal gene complement of Mycoplasma genitalium."; RL Science 270:397-403(1995). RN [2] RP SEQUENCE OF 108-130 FROM N.A. RC STRAIN=ATCC 33530 / G-37; RX MEDLINE; 94075230. RA Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III; RT "A survey of the Mycoplasma genitalium genome by using random RT sequencing."; RL J. Bacteriol. 175:7918-7930(1993). CC -!- FUNCTION: THIS ENZYME SCAVENGE EXOGENOUS AND ENDOGENOUS CYTIDINE CC AND 2'-DEOXYCYTIDINE FOR UMP SYNTHESIS (BY SIMILARITY). CC -!- CATALYTIC ACTIVITY: CYTIDINE + H(2)O = URIDINE + NH(3). CC -!- COFACTOR: TIGHTLY BIND A SINGLE ATOM OF ZINC (BY SIMILARITY). CC -!- SUBUNIT: HOMODIMER (BY SIMILARITY). CC -!- SIMILARITY: BELONGS TO THE CYTIDINE AND DEOXYCYTIDYLATE DEAMINASES CC FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U39684; AAC71268.1; -. DR EMBL; U02108; AAD12378.1; -. DR HSSP; P13652; 1AF2. DR TIGR; MG052; -. DR INTERPRO; IPR002125; -. DR PFAM; PF00383; dCMP_cyt_deam; 1. DR PROSITE; PS00903; CYT_DCMP_DEAMINASES; 1. KW Hydrolase; Zinc. FT METAL 54 54 ZINC (BY SIMILARITY). FT METAL 88 88 ZINC (BY SIMILARITY). FT METAL 91 91 ZINC (BY SIMILARITY). SQ SEQUENCE 130 AA; 14974 MW; 1DF02B1718F9495F CRC64; MKVNLEWIIK QLQMIVKRAY TPFSNFKVAC MIIANNQTFF GVNIENSSFP VTLCAERSAI ASMVTSGHRK IDYVFVYFNT KNKSNSPCGM CRQNLLEFSH QKTKLFCIDN DSSYKQFSID ELLMNGFKKS //