ID YJ9J_YEAST Reviewed; 342 AA. AC P47173; D6VWW1; DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot. DT 01-FEB-1996, sequence version 1. DT 22-FEB-2023, entry version 150. DE RecName: Full=Uncharacterized protein YJR142W; GN OrderedLocusNames=YJR142W; ORFNames=J2171; OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=559292; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 204508 / S288c; RX PubMed=8641269; DOI=10.1002/j.1460-2075.1996.tb00557.x; RA Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., RA Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., RA Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., RA Heumann K., Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., RA Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., RA Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., RA Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., RA Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., RA Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., RA To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., RA von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.; RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."; RL EMBO J. 15:2031-2049(1996). RN [2] RP GENOME REANNOTATION. RC STRAIN=ATCC 204508 / S288c; RX PubMed=24374639; DOI=10.1534/g3.113.008995; RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.; RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now."; RL G3 (Bethesda) 4:389-398(2014). RN [3] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 204508 / S288c; RX PubMed=17322287; DOI=10.1101/gr.6037607; RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J., RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., RA LaBaer J.; RT "Approaching a complete repository of sequence-verified protein-encoding RT clones for Saccharomyces cerevisiae."; RL Genome Res. 17:536-543(2007). RN [4] RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. RX PubMed=14562106; DOI=10.1038/nature02046; RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., RA O'Shea E.K., Weissman J.S.; RT "Global analysis of protein expression in yeast."; RL Nature 425:737-741(2003). CC -!- MISCELLANEOUS: Present with 217 molecules/cell in log phase SD medium. CC {ECO:0000269|PubMed:14562106}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z49642; CAA89675.1; -; Genomic_DNA. DR EMBL; AY558091; AAS56417.1; -; Genomic_DNA. DR EMBL; BK006943; DAA08927.1; -; Genomic_DNA. DR PIR; S57165; S57165. DR RefSeq; NP_012676.3; NM_001181800.3. DR AlphaFoldDB; P47173; -. DR SMR; P47173; -. DR BioGRID; 33898; 60. DR IntAct; P47173; 1. DR STRING; 4932.YJR142W; -. DR MaxQB; P47173; -. DR PaxDb; P47173; -. DR PeptideAtlas; P47173; -. DR EnsemblFungi; YJR142W_mRNA; YJR142W; YJR142W. DR GeneID; 853607; -. DR KEGG; sce:YJR142W; -. DR AGR; SGD:S000003903; -. DR SGD; S000003903; YJR142W. DR VEuPathDB; FungiDB:YJR142W; -. DR eggNOG; KOG4313; Eukaryota. DR GeneTree; ENSGT00390000016016; -. DR HOGENOM; CLU_048013_0_1_1; -. DR InParanoid; P47173; -. DR OMA; LQPECEY; -. DR OrthoDB; 1084242at2759; -. DR BioCyc; YEAST:G3O-31757-MON; -. DR BioGRID-ORCS; 853607; 1 hit in 10 CRISPR screens. DR PRO; PR:P47173; -. DR Proteomes; UP000002311; Chromosome X. DR RNAct; P47173; protein. DR GO; GO:0044715; F:8-oxo-dGDP phosphatase activity; IDA:SGD. DR CDD; cd03676; Nudix_hydrolase_3; 1. DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1. DR InterPro; IPR031804; DUF4743. DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf. DR InterPro; IPR000086; NUDIX_hydrolase_dom. DR PANTHER; PTHR13622; THIAMIN PYROPHOSPHOKINASE; 1. DR PANTHER; PTHR13622:SF8; THIAMIN PYROPHOSPHOKINASE 1; 1. DR Pfam; PF15916; DUF4743; 1. DR Pfam; PF00293; NUDIX; 1. DR SUPFAM; SSF55811; Nudix; 1. DR PROSITE; PS51462; NUDIX; 1. PE 1: Evidence at protein level; KW Reference proteome. FT CHAIN 1..342 FT /note="Uncharacterized protein YJR142W" FT /id="PRO_0000203126" FT DOMAIN 155..309 FT /note="Nudix hydrolase" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00794" SQ SEQUENCE 342 AA; 39690 MW; C0B14FD4DCCB1417 CRC64; MKVEKSSKGL EVLVRTQEDD LEGFSFLEIM DRVDPLPLDF ENYKNFKEGI YYMCTHDGTK IGFVLKFAIN EMETVCSEIF EETFQLDESR HELRFKSEDF DHRNNLIDQL ARKMYLESSL SGVKGWRNEK YAVWVNKKPY VLVERAVAGV LGIITYGIHI NGYVLDPKSK KVQFWVPRRS KTKQTWPLML DNIIAGGLGY PYGIYETVLK ESMEEANLEK SVIEDNIKAT GSVSYLYFTG DISVTKFNKE SDFIVGEVQY VYDLKLSEDI IPKPNDGEVE SFNLFSLQET INALRKKEFK PNCALVMVDF LIRHGYITPE NEPNYLELVT RMHRRLPFPT LN //