ID GTS1_ASCSU STANDARD; PRT; 205 AA. AC P46436; DT 01-NOV-1995 (Rel. 32, Created) DT 01-FEB-1996 (Rel. 33, Last sequence update) DT 01-NOV-1997 (Rel. 35, Last annotation update) DE GLUTATHIONE S-TRANSFERASE 1 (EC 2.5.1.18) (GST CLASS-SIGMA). GN GST1. OS Ascaris suum (Pig roundworm) (Ascaris lumbricoides). OC Eukaryota; Metazoa; Nematoda; Secernentea; Rhabditia; Ascaridida; OC Ascaridoidea; Ascarididae; Ascaris. RN [1] RP SEQUENCE FROM N.A., AND SEQUENCE OF 1-40. RX MEDLINE; 94239466. RA LIEBAU E., SCHOENBERGER O.L., WALTER R.D., HENKLE-DUEHRSEN K.J.; RT "Molecular cloning and expression of a cDNA encoding glutathione S- RT transferase from Ascaris suum."; RL Mol. Biochem. Parasitol. 63:167-170(1994). RN [2] RP SEQUENCE FROM N.A. RA LIEBAU E., ECKELT V., WILDENBERG G., TESSDALE-SPITTLE P., RA BROPHY P.M., WALTER R.D., HENKLE-DUEHRSEN K.; RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: CONJUGATION OF REDUCED GLUTATHIONE TO A WIDE NUMBER OF CC EXOGENOUS AND ENDOGENOUS HYDROPHOBIC ELECTROPHILES. CAN ALSO CC FUNCTION AS A GSH PEROXIDASE. CC -!- CATALYTIC ACTIVITY: RX + GLUTATHIONE = HX + R-S-GLUTATHIONE. CC -!- SIMILARITY: BELONGS TO THE GST SUPERFAMILY. SIGMA FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X75502; CAA53218.1; -. DR EMBL; Y10613; CAA71620.1; -. DR HSSP; P24472; 1GUK. DR PFAM; PF00043; GST; 1. KW Transferase. FT INIT_MET 0 0 SQ SEQUENCE 205 AA; 23454 MW; E6757B8E CRC32; PQYKLTYFDI RGLGEGARLI FHQAGVKFED NRLKREDWPA LKPKTPFGQL PLLEVDGEVL AQSAAIYRYL GRQFGLAGKT PMEEAQVDSI FDQFKDFMAE LRPCFRVLAG FEEGDKEKVL KEVAVPARDK HLPLLEKFLA KSGSEYMVGK SVTWADLVIT DSLASWESLI PDFLSGHLQL KKYIEHVREL PNIKKWIAER PKTPY //