ID GTS1_ASCSU STANDARD; PRT; 205 AA. AC P46436; DT 01-NOV-1995 (REL. 32, CREATED) DT 01-FEB-1996 (REL. 33, LAST SEQUENCE UPDATE) DT 01-NOV-1997 (REL. 35, LAST ANNOTATION UPDATE) DE GLUTATHIONE S-TRANSFERASE 1 (EC 2.5.1.18) (CLASS-SIGMA). GN GST1. OS ASCARIS SUUM (PIG ROUNDWORM) (ASCARIS LUMBRICOIDES). OC EUKARYOTA; METAZOA; NEMATODA; SECERNENTEA; RHABDITIA; ASCARIDIDA; OC ASCARIDOIDEA; ASCARIDIDAE; ASCARIS. RN [1] RP SEQUENCE FROM N.A., AND SEQUENCE OF 1-40. RX MEDLINE; 94239466. RA LIEBAU E., SCHOENBERGER O.L., WALTER R.D., HENKLE-DUEHRSEN K.J.; RT "Molecular cloning and expression of a cDNA encoding glutathione S- RT transferase from Ascaris suum."; RL MOL. BIOCHEM. PARASITOL. 63:167-170(1994). RN [2] RP SEQUENCE FROM N.A. RA LIEBAU E., ECKELT V., WILDENBERG G., TESSDALE-SPITTLE P., RA BROPHY P.M., WALTER R.D., HENKLE-DUEHRSEN K.; RL SUBMITTED (JAN-1997) TO EMBL/GENBANK/DDBJ DATA BANKS. CC -!- FUNCTION: CONJUGATION OF REDUCED GLUTATHIONE TO A WIDE NUMBER OF CC EXOGENOUS AND ENDOGENOUS HYDROPHOBIC ELECTROPHILES. CAN ALSO CC FUNCTION AS A GSH PEROXIDASE. CC -!- CATALYTIC ACTIVITY: RX + GLUTATHIONE = HX + R-S-G. CC -!- SIMILARITY: BELONGS TO THE GST SUPERFAMILY. SIGMA FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X75502; G415921; -. DR EMBL; Y10613; E293140; -. DR PFAM; PF00043; gluts; 1. DR HSSP; P24472; 1GUK. KW TRANSFERASE. FT INIT_MET 0 0 SQ SEQUENCE 205 AA; 23454 MW; E6757B8E CRC32; PQYKLTYFDI RGLGEGARLI FHQAGVKFED NRLKREDWPA LKPKTPFGQL PLLEVDGEVL AQSAAIYRYL GRQFGLAGKT PMEEAQVDSI FDQFKDFMAE LRPCFRVLAG FEEGDKEKVL KEVAVPARDK HLPLLEKFLA KSGSEYMVGK SVTWADLVIT DSLASWESLI PDFLSGHLQL KKYIEHVREL PNIKKWIAER PKTPY //