ID PPSA_PYRFU STANDARD; PRT; 817 AA. AC P42850; DT 01-NOV-1995 (REL. 32, CREATED) DT 01-FEB-1996 (REL. 33, LAST SEQUENCE UPDATE) DT 01-FEB-1996 (REL. 33, LAST ANNOTATION UPDATE) DE PROBABLE PHOSPHOENOLPYRUVATE SYNTHASE (EC 2.7.9.2) (PYRUVATE,WATER DE DIKINASE) (PEP SYNTHASE). OS PYROCOCCUS FURIOSUS. OC ARCHAEBACTERIA; CRENARCHAEOTA; THERMOPROTEALES; THERMOCOCCACEAE. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=DSM 3638; RX MEDLINE; 95129854. RA ROBINSON K.A., SCHREIER H.J.; RL GENE 151:173-176(1994). CC -!- PATHWAY: ESSENTIAL STEP IN GLUCONEOGENESIS WHEN PYRUVATE AND CC LACTATE ARE USED AS A CARBON SOURCE. CC -!- CATALYTIC ACTIVITY: ATP + PYRUVATE + H(2)O = AMP + CC PHOSPHOENOLPYRUVATE + PHOSPHATE. CC -!- SIMILARITY: TO OTHER PEP-UTILIZING ENZYMES. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U08376; G1066016; -. DR PROSITE; PS00370; PEP_ENZYMES_PHOS_SITE. DR PROSITE; PS00742; PEP_ENZYMES_2. KW TRANSFERASE; KINASE; ATP-BINDING; PHOSPHORYLATION. FT MOD_RES 442 442 PHOSPHORYLATION (BY SIMILARITY). FT DOMAIN 809 815 POLY-GLU. SQ SEQUENCE 817 AA; 90485 MW; 6236657C CRC32; MAYRFIKWFE ELSKNDVPLV GGKGANLGEM TNAGIPVPPG FCVTAEAYKY FVENVKVSKE DVKRILGEKV NKGTISEVLA QAPDEPRPLQ DWIMDIISKT DVDDSKMLQE NTEAIRTLIK SLDMPSEIAE EIKQAYKELS QRFGQEEVYV AVRSSATAED LPEASFAGQQ ETYLDVLGAD DVIDKVKRCW ASLWTARATF YRAKQGFDHS KVYLSAVVQK MVNSEKSGVM FTANPVTNNR NEIMINASWG LGEAVVSGAV TPDEYIVEKG TWKIKEKVIA KKEVMVIRNP ETGRGTVMVK VAEYLGPEWV EKQVLTDEQI IEVAKMGQKI EDHYGWPQDI EWAYDKDDGK LYIVQSRPIT TLKEEATAEE AEEVEEAEVI LKGLGASPGI GAGRVVVIFD ASEIDKVKEG DILVTTMTNP DMVPAMKRAA AIVTDEGGRT SHAAIVSREL GIPCVVGTKE ATKKLKTGMY VTVDGTRGLV YKGIVKSLVK KKEEAKAEGG QVVVAGAPLV TGTMVKVNVS MPEVAERAAA TGADGVGLLR AEHMILSIGQ HPIKFIKEGK EEELVEKLAE GIEKVAAAFY PRPVWYRTLD APTNEFREMP GGEDEPEERN PMLGWRGIRR GLDQPELLRA EFKAIKKVVE KGYNNIGVML PLVSHPEQIR EAKRIAREVG LEPHKDVAWG VMIEVPAAAI IIEDLIKEGI DFVSFGTNDL TQYTLAIDRD NERVAKLYDE THPAVLKLIK HVIKVCQRYG VETSICGQAG SDPKMARILV RLGIDSISAN PDAVQLIRQV VAQEERKLML EAARKQLFEE EEEEELF //