ID PPSA_PYRFU STANDARD; PRT; 794 AA. AC P42850; DT 01-NOV-1995 (REL. 32, CREATED) DT 01-NOV-1995 (REL. 32, LAST SEQUENCE UPDATE) DT 01-NOV-1995 (REL. 32, LAST ANNOTATION UPDATE) DE PROBABLE PHOSPHOENOLPYRUVATE SYNTHASE (EC 2.7.9.2) (PYRUVATE,WATER DE DIKINASE) (PEP SYNTHASE). OS PYROCOCCUS FURIOSUS. OC ARCHAEBACTERIA; CRENARCHAEOTA; THERMOPROTEALES; THERMOCOCCACEAE. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=DSM 3638; RA ROBINSON K.A., SCHREIER H.J.; RL GENE 151:173-176(1994). CC -!- PATHWAY: ESSENTIAL STEP IN GLUCONEOGENESIS WHEN PYRUVATE AND CC LACTATE ARE USED AS A CARBON SOURCE. CC -!- CATALYTIC ACTIVITY: ATP + PYRUVATE + H(2)O = AMP + CC PHOSPHOENOLPYRUVATE + PHOSPHATE. CC -!- SIMILARITY: TO OTHER PEP-UTILIZING ENZYMES. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U08376; U08376. DR PROSITE; PS00370; PEP_ENZYMES_PHOS_SITE. DR PROSITE; PS00742; PEP_ENZYMES_2. KW TRANSFERASE; KINASE; ATP-BINDING; PHOSPHORYLATION. FT MOD_RES 412 412 PHOSPHORYLATION (BY SIMILARITY). SQ SEQUENCE 794 AA; 87954 MW; 3181169 CN; MAYRFIKWFE ELSKNDVPLV GGKGANLGEM TNAGILGEKV NKGTISEVLA QAPDEPRPLQ DWIMDIISKT DVDDSKMLQE NTEAIRTLIK SLDMPSEIAE EIKQAYKELS QRFGQEEVYV AVRSSATAED LPEASFAGQQ ETYLDVLGAD DVIDKVKRCW ASLWTPRATF YRAKQGFDHS KVYLSAVVQK MVNSEKSGVM FTANPVTNNR NEIMINASWG LGEAVVSGAV TPDEYIVEKG TWKIKEKVIA KKEVMVIRNP ETGRGTVMVK VAEYLGPEWV EKQVLTDEQI IEVAKMGQKI EDHYGWPQDI EWAYDKDDGK LYIVQSRPIT TLKEEATAEE AEEVEEAEVI LKGLGASPGI GAGRVVVIFD ASEIDKVKEG DILVTTMTNP DMVPAMKRAA AIVTDEGGRT SHAAIVSREL GIPCVLETKE ATKKLKTGMY VTVDGTRGLV YKGIVKSLVK KKEEAKAEGG QVVVAGAPLV TGTMVKVNVS MPEVAERAAA TGADGVGLLR AEHMILSIGQ HPIKFIKEGK EEELVEKLAE GIEKVAAAFY PRPVWYRTLD APTNEFREMP GGEDEPEERN PMLGWRGIRR GLDQPELLRA EFKAIKKVVE KGYNNIGVML PLVSHPEQIR EAKRIAREVG LEPHKDVAWG VMIEVPAAAI IIEDLIKEGI DFVSFGTNDL TQYTLAIDRD NERVAKLYDE THPAVLKLIK HVIKVCQRYG VETSICGQAG SDPKMARILV RLGIDSISAN PDAVQLIRQV VAQEERKLML EAARKQLFEK RKKRSSSEVF PPFL //