ID NU4LM_BALMU Reviewed; 98 AA. AC P41301; DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot. DT 01-FEB-1995, sequence version 1. DT 31-MAY-2011, entry version 56. DE RecName: Full=NADH-ubiquinone oxidoreductase chain 4L; DE EC=1.6.5.3; DE AltName: Full=NADH dehydrogenase subunit 4L; GN Name=MT-ND4L; Synonyms=MTND4L, NADH4L, ND4L; OS Balaenoptera musculus (Blue whale). OG Mitochondrion. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Cetacea; OC Mysticeti; Balaenopteridae; Balaenoptera. OX NCBI_TaxID=9771; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX MEDLINE=94141932; PubMed=8308901; RA Arnason U., Gullberg A.; RT "Comparison between the complete mtDNA sequences of the blue and the RT fin whale, two species that can hybridize in nature."; RL J. Mol. Evol. 37:312-322(1993). CC -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory CC chain NADH dehydrogenase (Complex I) that is believed to belong to CC the minimal assembly required for catalysis. Complex I functions CC in the transfer of electrons from NADH to the respiratory chain. CC The immediate electron acceptor for the enzyme is believed to be CC ubiquinone (By similarity). CC -!- CATALYTIC ACTIVITY: NADH + ubiquinone = NAD(+) + ubiquinol. CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane; Multi-pass membrane CC protein (By similarity). CC -!- SIMILARITY: Belongs to the complex I subunit 4L family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X72204; CAA51003.1; -; Genomic_DNA. DR PIR; S41828; S41828. DR RefSeq; NP_007064.1; NC_001601.1. DR GeneID; 807737; -. DR CTD; 807737; -. DR HOVERGEN; HBG071122; -. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:EC. DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro. DR GO; GO:0006810; P:transport; IEA:UniProtKB-KW. DR InterPro; IPR001133; NADH_UbQ_OxRdtase_chain4L/K. DR PANTHER; PTHR11434; Oxidored_4L; 1. DR Pfam; PF00420; Oxidored_q2; 1. PE 3: Inferred from homology; KW Electron transport; Membrane; Mitochondrion; NAD; Oxidoreductase; KW Respiratory chain; Transmembrane; Transmembrane helix; Transport; KW Ubiquinone. FT CHAIN 1 98 NADH-ubiquinone oxidoreductase chain 4L. FT /FTId=PRO_0000118394. FT TRANSMEM 1 21 Helical; (Potential). FT TRANSMEM 29 49 Helical; (Potential). FT TRANSMEM 61 81 Helical; (Potential). SQ SEQUENCE 98 AA; 10747 MW; 9F770651FE65ED1B CRC64; MTLIHMNVLM AFSMSLVGLL MYRSHLMSAL LCLEGMMLSL FVLAALTILN SHFTLANMMP IILLVFAAYV AAIGLALLVM VSNTYGTDYV QSLNLLQC //