ID CYAA_HAEIN STANDARD; PRT; 843 AA. AC P40134; DT 01-FEB-1995 (REL. 31, CREATED) DT 01-FEB-1995 (REL. 31, LAST SEQUENCE UPDATE) DT 01-NOV-1995 (REL. 32, LAST ANNOTATION UPDATE) DE ADENYLATE CYCLASE (EC 4.6.1.1) (ATP PYROPHOSPHATE-LYASE) (ADENYLYL DE CYCLASE). GN CYAA OR CYA OR HI0604. OS HAEMOPHILUS INFLUENZAE. OC PROKARYOTA; GRACILICUTES; SCOTOBACTERIA; FACULTATIVELY ANAEROBIC RODS; OC PASTEURELLACEAE. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=RD; RX MEDLINE; 94042886. RA DOROCICZ I.R., WILLIAMS P.M., REDFIELD R.J.; RL J. BACTERIOL. 175:7142-7149(1993). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=RD / KW20; RA FLEISCHMANN R.D., ADAMS M.D., WHITE O., CLAYTON R.A., KIRKNESS E.F., RA KERLAVAGE A.R., BULT C.J., TOMB J.-F., DOUGHERTY B.A., MERRICK J.M., RA MCKENNEY K., SUTTON G., FITZHUGH W., FIELDS C.A., GOCAYNE J.D., RA SCOTT J.D., SHIRLEY R., LIU L.-I., GLODEK A., KELLEY J.M., RA WEIDMAN J.F., PHILLIPS C.A., SPRIGGS T., HEDBLOM E., COTTON M.D., RA UTTERBACK T.R., HANNA M.C., NGUYEN D.T., SAUDEK D.M., BRANDON R.C., RA FINE L.D., FRITCHMAN J.L., FUHRMANN J.L., GEOGHAGEN N.S.M., RA GNEHM C.L., MCDONALD L.A., SMALL K.V., FRASER C.M., SMITH H.O., RA VENTER J.C.; RL SCIENCE 269:496-512(1995). CC -!- CATALYTIC ACTIVITY: ATP = 3',5'-CYCLIC AMP + PYROPHOSPHATE. CC -!- SIMILARITY: CYTOPLASMIC. CC -!- SIMILARITY: BELONGS TO CLASS-1 OF ADENYLYL CYCLASES. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L23824; L23824. DR EMBL; U32742; U32742. DR PIR; A49922; A49922. DR PROSITE; PS01092; ADENYLATE_CYCLASE_1_1. DR PROSITE; PS01093; ADENYLATE_CYCLASE_1_2. KW LYASE; CAMP SYNTHESIS. FT DOMAIN 1 542 CATALYTIC (POTENTIAL). FT DOMAIN 549 843 REGULATORY (POTENTIAL). SQ SEQUENCE 843 AA; 97926 MW; 3610770 CN; MECNLAQAKQ WVSALDQRRF ERALQGSGDA FQHVLAIVPL LLHLNHPQLP GYVIHAPSGI ASFLASDYQK KWLTNEYGIH YADHKPSTLK SAVNFHEVFP PILGVYVMGS FGSISQTSSS DLDTWICVRD GLSLDEYTLL TQKAKRISEW AMQFNVEINF YLMDQQRFRN EHYADPLTIE NSGSAQYMLL LDEFYRSAVR LAGKPLLWLH LWVENEKDYE KEVARLITEG EIDPNDWVDF GGLGQFSANE YFGASLWHLY KGIDSPYKSV LKILLLEAYS KEYPNTCLIA RTFKRDLLAG NTNPDHHFDP YIAILAKVTQ YLTALSEFKR LDFVHRCFYV KATEDFARYQ ANNWRIRYME ILAQEWGWSA ETVKHLNKRP FWKIKAVKEN HDNIMKFLML SYRNLVEFAR KHHIHSSVVP QDINILSRKL YTAFEELPGK VSLLNTQISH NLSEAHLTFV EVRGNKHFKD GWYLINQPIH HIMFSKERVI EYGESLNKLV SWAYFNHLLT EKTELSIFSK NVTLSTLQRF VTNLRQSFPS TIAKQPKNSD LLNQCEIRSL FIAINLTTDP TSKVEEVLTG ISSRDLFSFG SLEQSLVGSI DFTYRNVWNE IRTLHFEGQN AILLALKVLS NKIYRGVNRP DSIQVYCYSE RYRQDLRQLV MGLVNRCVSI QVGDIQQPCQ TSRLRVAGKN WQLFFEDRGI SLQEIGNESV CNEAESAVDF DEVLQTPIED GETNQESRRY PPEMDAFASE GFLQFFFEDN SDHSFNVYIL DESNHLEIYR HCDGEKDEKV REINQLYQNA KQEGDKNPYN IVQHNFNYPQ FYQLQNGKNG ISIVPFKFRQ MNK //