ID YH02_YEAST Reviewed; 602 AA. AC P38887; D3DLF1; DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot. DT 01-FEB-1995, sequence version 1. DT 24-JUL-2024, entry version 156. DE RecName: Full=Uncharacterized protein YHR202W; GN OrderedLocusNames=YHR202W; OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=559292; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 204508 / S288c; RX PubMed=8091229; DOI=10.1126/science.8091229; RA Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., RA Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., RA Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P., Louis E.J., RA Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., RA St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., RA Waterston R., Wilson R., Vaudin M.; RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome RT VIII."; RL Science 265:2077-2082(1994). RN [2] RP GENOME REANNOTATION. RC STRAIN=ATCC 204508 / S288c; RX PubMed=24374639; DOI=10.1534/g3.113.008995; RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.; RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now."; RL G3 (Bethesda) 4:389-398(2014). RN [3] RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]. RX PubMed=14562095; DOI=10.1038/nature02026; RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., RA Weissman J.S., O'Shea E.K.; RT "Global analysis of protein localization in budding yeast."; RL Nature 425:686-691(2003). RN [4] RP GLYCOSYLATION [LARGE SCALE ANALYSIS]. RX PubMed=19756047; DOI=10.1038/msb.2009.64; RA Kung L.A., Tao S.-C., Qian J., Smith M.G., Snyder M., Zhu H.; RT "Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals RT new roles for protein glycosylation in eukaryotes."; RL Mol. Syst. Biol. 5:308-308(2009). CC -!- SUBCELLULAR LOCATION: Vacuole {ECO:0000269|PubMed:14562095}. CC -!- PTM: N-glycosylated. {ECO:0000269|PubMed:19756047}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U00030; AAB68354.1; -; Genomic_DNA. DR EMBL; BK006934; DAA06895.1; -; Genomic_DNA. DR PIR; S46676; S46676. DR RefSeq; NP_012072.3; NM_001179333.3. DR AlphaFoldDB; P38887; -. DR SMR; P38887; -. DR BioGRID; 36636; 67. DR IntAct; P38887; 2. DR STRING; 4932.YHR202W; -. DR GlyGen; P38887; 3 sites. DR PaxDb; 4932-YHR202W; -. DR PeptideAtlas; P38887; -. DR EnsemblFungi; YHR202W_mRNA; YHR202W; YHR202W. DR GeneID; 856609; -. DR KEGG; sce:YHR202W; -. DR AGR; SGD:S000001245; -. DR SGD; S000001245; YHR202W. DR VEuPathDB; FungiDB:YHR202W; -. DR eggNOG; KOG4419; Eukaryota. DR GeneTree; ENSGT00530000063775; -. DR HOGENOM; CLU_019028_0_0_1; -. DR InParanoid; P38887; -. DR OMA; PISFYRV; -. DR OrthoDB; 5490776at2759; -. DR BioCyc; YEAST:G3O-31229-MONOMER; -. DR BioGRID-ORCS; 856609; 0 hits in 10 CRISPR screens. DR PRO; PR:P38887; -. DR Proteomes; UP000002311; Chromosome VIII. DR RNAct; P38887; Protein. DR GO; GO:0005829; C:cytosol; IDA:SGD. DR GO; GO:0005576; C:extracellular region; IDA:SGD. DR GO; GO:0000324; C:fungal-type vacuole; HDA:SGD. DR GO; GO:0008253; F:5'-nucleotidase activity; ISS:SGD. DR GO; GO:0019677; P:NAD catabolic process; IMP:SGD. DR CDD; cd07407; MPP_YHR202W_N; 1. DR Gene3D; 3.60.21.10; -; 1. DR Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 2. DR InterPro; IPR036907; 5'-Nucleotdase_C_sf. DR InterPro; IPR006179; 5_nucleotidase/apyrase. DR InterPro; IPR029052; Metallo-depent_PP-like. DR InterPro; IPR014485; Pesterase_C1039. DR InterPro; IPR041823; YHR202W_N. DR PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1. DR PANTHER; PTHR11575:SF22; METALLOPHOS DOMAIN-CONTAINING PROTEIN; 1. DR PIRSF; PIRSF017316; Pesterase_C1039; 1. DR SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1. DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1. PE 1: Evidence at protein level; KW Glycoprotein; Reference proteome; Vacuole. FT CHAIN 1..602 FT /note="Uncharacterized protein YHR202W" FT /id="PRO_0000202941" FT CARBOHYD 305 FT /note="N-linked (GlcNAc...) asparagine" FT /evidence="ECO:0000255" FT CARBOHYD 497 FT /note="N-linked (GlcNAc...) asparagine" FT /evidence="ECO:0000255" FT CARBOHYD 577 FT /note="N-linked (GlcNAc...) asparagine" FT /evidence="ECO:0000255" SQ SEQUENCE 602 AA; 68998 MW; B9A69DAA3DD0A702 CRC64; MILKLVHCLV ALTGLIFAKP YQQQQAVLAP SQDVPLRDIH IGDINFIHTT DTHGWLGSHL SQNDYDADWG DFVAFVDILR EKILRQSRDV IVIDTGDKRD GNGLSDATWP PGLRSSEIFN MMDYDLLTLG NHELYTAESA ILEYRGTSQS SKFKDKYVCS NVEFIEDDGT RVPFGNKYIT FETPIMKQRV LALSFLFSFQ RANNRAIVTP PLEEITQKSW FQNMVETNRE EEIDLIIVFG HLPATDPTER EMHKIHALIR KYYPNTVIQY FGGHTHIRDF VQLDSKSTCL QSGRFAETVG FLSINMTDPV DAESPIFSRR YIDFNKEAFK YHLSKLGHDS NVPVSTKKGK TISRLVNDLR HELNLNEKLG YIPQTYYVST RPLNSEENLY HLITHKILPN LIPPKNYEPS MSRFILINTG SVRYDLYKGP FTKDTEYIVM PFNNDWRFIT VPLVVASRVE TYLNKGPVIA SLGIPSSSHH KQHFGGFQKC PFINNPNLSE GYTTEDDFGC HGDDTPHNSQ REYDIPNVVQ CKEVKKVQEE EADPSKMVHV IFYSFMELDI LNAVNSIIND LGLRMENLTT NDCSHYGGDS TKKLLRDYFS QF //