ID ADY1_YEAST Reviewed; 237 AA. AC P38872; DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot. DT 01-FEB-1995, sequence version 1. DT 04-NOV-2008, entry version 50. DE RecName: Full=Prospore formation at selected spindle poles protein 1; DE AltName: Full=Accumulates dyads protein 1; GN Name=PFS1; Synonyms=ADY1; OrderedLocusNames=YHR185C; OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 204511 / S288c / AB972; RX MEDLINE=94378003; PubMed=8091229; RA Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., RA Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., RA Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., RA Latreille P., Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., RA Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., RA Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., RA Vaudin M.; RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome RT VIII."; RL Science 265:2077-2082(1994). RN [2] RP FUNCTION, AND SUBCELLULAR LOCATION. RX MEDLINE=21437857; PubMed=11553705; RA Deng C., Saunders W.S.; RT "ADY1, a novel gene required for prospore membrane formation at RT selected spindle poles in Saccharomyces cerevisiae."; RL Mol. Biol. Cell 12:2646-2659(2001). CC -!- FUNCTION: Involved in the pathway that organizes the shaping and CC sizing of the prospore membrane (PSM) during sporulation. Required CC to localize MPC54 to all four spindle pole bodies, and localize CC DON1 and SPO14 to four prospore membranes. CC -!- INTERACTION: CC P29295:HRR25; NbExp=1; IntAct=EBI-24859, EBI-8536; CC P40555:NAS2; NbExp=2; IntAct=EBI-24859, EBI-14024; CC -!- SUBCELLULAR LOCATION: Nucleus. Note=Nuclear in mononucleate CC meiotic cells. May not be localized to the spindle pole body or CC prospore membrane. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U00030; AAB68363.1; -; Genomic_DNA. DR PIR; S46685; S46685. DR RefSeq; NP_012055.1; -. DR DIP; DIP:1372N; -. DR IntAct; P38872; -. DR Ensembl; YHR185C; Saccharomyces cerevisiae. DR GeneID; 856591; -. DR GenomeReviews; U00093_GR; YHR185C. DR KEGG; sce:YHR185C; -. DR NMPDR; fig|4932.3.peg.3224; -. DR CYGD; YHR185c; -. DR SGD; S000001228; PFS1. DR HOGENOM; P38872; -. DR LinkHub; P38872; -. DR NextBio; 982470; -. DR GermOnline; YHR185C; Saccharomyces cerevisiae. DR GO; GO:0005515; F:protein binding; IPI:IntAct. DR GO; GO:0030476; P:ascospore wall assembly; IMP:SGD. PE 1: Evidence at protein level; KW Complete proteome; Nucleus; Sporulation. FT CHAIN 1 237 Prospore formation at selected spindle FT poles protein 1. FT /FTId=PRO_0000064460. SQ SEQUENCE 237 AA; 27884 MW; 027F01058C0CFE6E CRC64; MNQGYTQLSA PELKETKTSK LNKMNNFRSS PIAEIINKIP PDCGKIQNTT FPEFNPALRR RQHEQWPAYE KPIRVTDSMS PQLSSINCLP NLYPHGTLPL PNPYLSYLNH IEKVNCQDVK FSNWSVLHNS NNGFEIPTYF SPRTTQNMPC SEKVESWLER LPIFVGFDGY LFTNCFDYEY MLDWEETEFT FEKTSCMETD YSKALTDTDI IYIQEKKIEA LIRNQYLKEY EFSQKDF //