ID MUM2_YEAST Reviewed; 366 AA. AC P38236; DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot. DT 01-OCT-1994, sequence version 1. DT 23-MAR-2010, entry version 62. DE RecName: Full=Protein MUM2; DE AltName: Full=Muddled meiosis protein 2; GN Name=MUM2; OrderedLocusNames=YBR057C; ORFNames=YBR0514; OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomyceta; OC Saccharomycotina; Saccharomycetes; Saccharomycetales; OC Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 204508 / S288c; RX MEDLINE=95321020; PubMed=7597852; DOI=10.1002/yea.320110511; RA Aljinovic G., Pohl T.M.; RT "Sequence and analysis of 24 kb on chromosome II of Saccharomyces RT cerevisiae."; RL Yeast 11:475-479(1995). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 204508 / S288c; RX MEDLINE=95112788; PubMed=7813418; RA Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., RA Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., RA Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., RA Cziepluch C., Demolis N., Delaveau T., Doignon F., Domdey H., RA Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., RA Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., RA Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., RA Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., RA Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., RA Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., RA Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., RA Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., RA Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., RA Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., RA Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., RA Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., RA van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., RA Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., RA Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.; RT "Complete DNA sequence of yeast chromosome II."; RL EMBO J. 13:5795-5809(1994). RN [3] RP DISRUPTION PHENOTYPE. RX PubMed=12586695; RA Enyenihi A.H., Saunders W.S.; RT "Large-scale functional genomic analysis of sporulation and meiosis in RT Saccharomyces cerevisiae."; RL Genetics 163:47-54(2003). RN [4] RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. RX MEDLINE=22923965; PubMed=14562106; DOI=10.1038/nature02046; RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., RA Dephoure N., O'Shea E.K., Weissman J.S.; RT "Global analysis of protein expression in yeast."; RL Nature 425:737-741(2003). CC -!- INTERACTION: CC Self; NbExp=1; IntAct=EBI-11619, EBI-11619; CC -!- DISRUPTION PHENOTYPE: Mutant is sporulation defective and fails to CC perform premeiotic DNA synthesis. CC -!- MISCELLANEOUS: Present with 3400 molecules/cell in log phase SD CC medium. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z35926; CAA85000.1; -; Genomic_DNA. DR EMBL; Z46260; CAA86401.1; -; Genomic_DNA. DR PIR; S45915; S45915. DR RefSeq; NP_009613.1; -. DR DIP; DIP-1299N; -. DR IntAct; P38236; 18. DR MINT; MINT-399622; -. DR STRING; P38236; -. DR PRIDE; P38236; -. DR Ensembl; YBR057C; YBR057C; YBR057C; Saccharomyces cerevisiae. DR GeneID; 852348; -. DR GenomeReviews; Y13134_GR; YBR057C. DR KEGG; sce:YBR057C; -. DR NMPDR; fig|4932.3.peg.309; -. DR CYGD; YBR057c; -. DR SGD; S000000261; MUM2. DR eggNOG; fuNOG10680; -. DR OrthoDB; EOG9FFFJH; -. DR PhylomeDB; P38236; -. DR NextBio; 971092; -. DR ArrayExpress; P38236; -. DR Genevestigator; P38236; -. DR GermOnline; YBR057C; Saccharomyces cerevisiae. DR GO; GO:0005737; C:cytoplasm; IDA:SGD. DR GO; GO:0042802; F:identical protein binding; IPI:IntAct. DR GO; GO:0007126; P:meiosis; IEA:UniProtKB-KW. DR GO; GO:0006279; P:premeiotic DNA synthesis; IMP:SGD. PE 1: Evidence at protein level; KW Complete proteome; Meiosis. FT CHAIN 1 366 Protein MUM2. FT /FTId=PRO_0000096647. SQ SEQUENCE 366 AA; 41433 MW; E57C853BFE8E5E83 CRC64; MNYMAYDYDP QHSLETSFNN LAFHPHQQSQ QQALYESGER NDARPGLMNT LGQASKMNNS MLPQGSSASP LTGQHSLNST TNFNMPPSMN TYNYQNVPQA SMRNTLNHNN IMNGATANDY WLDPMNNMTN NKDTNGNPND SMSSMSNMTA KTSINSTAFK NSFVPFNHVT ALSMNNVNSN EMNSNKDDRM EALEVELQIK ESQIESLENE IQRLKKIFNE GLNYKQNEHK YEKENCHIPQ TFELPASLEV IFRKLSSSLH AKEKELAETK ENLESILTAL ALNPTNSVTK YGRYDAESIA HKMVVRLENL TNENKEMAKM LAYGRSKETQ IELQLAKKEN LELREKIASL EAHLASKESS KEDVAN //