ID CUE2_YEAST STANDARD; PRT; 443 AA. AC P36075; DT 01-JUN-1994 (Rel. 29, Created) DT 01-JUN-1994 (Rel. 29, Last sequence update) DT 01-OCT-2004 (Rel. 45, Last annotation update) DE CUE2 protein. GN Name=CUE2; OrderedLocusNames=YKL090W; OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932; RN [1] RP SEQUENCE FROM N.A. RX PubMed=8196765; DOI=10.1038/369371a0; RA Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., RA Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., RA Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., RA Daignan-Fornier B., del Rey F., Dion C., Domdey H., Duesterhoeft A., RA Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., RA Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., RA Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., RA Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., RA Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., RA Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., RA Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., RA Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., RA Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., RA Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., RA Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., RA Remacha M., Revuelta J.L., Richard G.-F., Rieger M., RA Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., RA Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., RA Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., RA van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., RA Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., RA Zimmermann J., Haasemann M., Becker I., Mewes H.-W.; RT "Complete DNA sequence of yeast chromosome XI."; RL Nature 369:371-378(1994). RN [2] RP STRUCTURE BY NMR OF 1-54 IN COMPLEX WITH UBIQUITIN. RX PubMed=12787503; RA Kang R.S., Daniels C.M., Francis S.A., Shih S.C., Salerno W.J., RA Hicke L., Radhakrishnan I.; RT "Solution structure of a CUE-ubiquitin complex reveals a conserved RT mode of ubiquitin binding."; RL Cell 113:621-630(2003). CC -!- SUBUNIT: Binds to ubiquitin. CC -!- SIMILARITY: Contains 2 CUE domains. CC -!- SIMILARITY: Contains 1 Smr domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z28090; CAA81928.1; -. DR PIR; S37915; S37915. DR PDB; 1OTR; NMR; A=6-54. DR GermOnline; 139846; -. DR SGD; S0001573; CUE2. DR GO; GO:0005515; F:protein binding; IDA. DR InterPro; IPR003892; CUE. DR InterPro; IPR002625; Smr/MutS2_C. DR Pfam; PF02845; CUE; 2. DR SMART; SM00546; CUE; 2. DR SMART; SM00463; SMR; 1. DR PROSITE; PS50828; SMR; 1. KW 3D-structure; Repeat; Ubl conjugation pathway. FT DOMAIN 8 50 CUE 1. FT DOMAIN 55 97 CUE 2. FT DOMAIN 347 443 Smr. SQ SEQUENCE 443 AA; 50873 MW; 8B7BB872C2BDC734 CRC64; MSMDNNDDHE SKLSILMDMF PAISKSKLQV HLLENNNDLD LTIGLLLKEN DDKSTVDNEL HQLYDMFPQL DCSVIKDQFV INEKSVESTI SDLLNYETLQ KLKDNQANSP DSVKRNEKKN NWESTNDHIE SIIKFTDAPK NIAQEYLAEN GFDTVKAIIK IILDYYDKRD FKKDVDTFKV KRSPNTTVRG GRVQSSTGLA HVLKKGKESA NVAQESLKRP RSYKHSLDSP QMVELNELVA DNRDLKAINH EFLQKCLQFY DGDVVKVLNI SSLLIEDDKN ITKTWNFDEG FTLTSRDNCK QHLPKFSTPQ ISRRNEVGNT YKLPLHDKET PEGAVPVINN LFQTYRLDFH GFLPSEAVST LKLALNKWWS KEVAERELNS HNINSYGSKV QFVSPLIVVT GRGIHSIGGI SKVRLQVKSF LEKNHYIFWE ESSYFRIEGK KKK //