ID UBC7_CAEEL STANDARD; PRT; 164 AA. AC P34477; DT 01-FEB-1994 (Rel. 28, Created) DT 01-FEB-1994 (Rel. 28, Last sequence update) DT 15-MAR-2004 (Rel. 43, Last annotation update) DE Probable ubiquitin-conjugating enzyme E2-19 kDa (EC 6.3.2.19) DE (Ubiquitin-protein ligase) (Ubiquitin carrier protein). GN F58A4.10. OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; OC Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=6239; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=Bristol N2; RX MEDLINE=94150718; PubMed=7906398; RA Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., RA Bonfield J., Burton J., Connell M., Copsey T., Cooper J., Coulson A., RA Craxton M., Dear S., Du Z., Durbin R., Favello A., Fraser A., RA Fulton L., Gardner A., Green P., Hawkins T., Hillier L., Jier M., RA Johnston L., Jones M., Kershaw J., Kirsten J., Laisster N., RA Latreille P., Lightning J., Lloyd C., Mortimore B., O'Callaghan M., RA Parsons J., Percy C., Rifken L., Roopra A., Saunders D., Shownkeen R., RA Sims M., Smaldon N., Smith A., Smith M., Sonnhammer E., Staden R., RA Sulston J., Thierry-Mieg J., Thomas K., Vaudin M., Vaughan K., RA Waterston R., Watson A., Weinstock L., Wilkinson-Sproat J., RA Wohldman P.; RT "2.2 Mb of contiguous nucleotide sequence from chromosome III of C. RT elegans."; RL Nature 368:32-38(1994). CC -!- FUNCTION: Catalyzes the covalent attachment of ubiquitin to other CC proteins (By similarity). CC -!- CATALYTIC ACTIVITY: ATP + ubiquitin + protein lysine = AMP + CC diphosphate + protein N-ubiquityllysine. CC -!- PATHWAY: Ubiquitin conjugation; second step. CC -!- MISCELLANEOUS: A cysteine residue is required for ubiquitin- CC thiolester formation (By similarity). CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. CC STRONGEST, TO YEAST UBC1. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z22179; CAA80166.1; -. DR PIR; S40982; S40982. DR PDB; 1PZV; 22-JUL-03. DR WormPep; F58A4.10; CE00216. DR InterPro; IPR000608; UBQ_conjugat. DR Pfam; PF00179; UQ_con; 1. DR ProDom; PD000461; UBQ_conjugat; 1. DR SMART; SM00212; UBCc; 1. DR PROSITE; PS00183; UBIQUITIN_CONJUGAT_1; 1. DR PROSITE; PS50127; UBIQUITIN_CONJUGAT_2; 1. KW Ubl conjugation pathway; Ligase; Multigene family; 3D-structure. FT BINDING 88 88 Ubiquitin (By similarity). SQ SEQUENCE 164 AA; 18938 MW; 62580D9F3F8FD968 CRC64; MEQSSLLLKK QLADMRRVPV DGFSAGLVDD NDIYKWEVLV IGPPDTLYEG GFFKAILDFP RDYPQKPPKM KFISEIWHPN IDKEGNVCIS ILHDPGDDKW GYERPEERWL PVHTVETILL SVISMLTDPN FESPANVDAA KMQRENYAEF KKKVAQCVRR SQEE //