ID NU133_CAEEL Reviewed; 1129 AA. AC P34343; Q5WRU8; DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot. DT 25-JAN-2012, sequence version 4. DT 22-FEB-2012, entry version 82. DE RecName: Full=Nuclear pore complex protein 15; DE AltName: Full=Nucleoporin npp-15; GN Name=npp-15; Synonyms=nup133; ORFNames=C29E4.4; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; OC Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=6239; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2; RX MEDLINE=94150718; PubMed=7906398; DOI=10.1038/368032a0; RA Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., RA Bonfield J., Burton J., Connell M., Copsey T., Cooper J., Coulson A., RA Craxton M., Dear S., Du Z., Durbin R., Favello A., Fraser A., RA Fulton L., Gardner A., Green P., Hawkins T., Hillier L., Jier M., RA Johnston L., Jones M., Kershaw J., Kirsten J., Laisster N., RA Latreille P., Lightning J., Lloyd C., Mortimore B., O'Callaghan M., RA Parsons J., Percy C., Rifken L., Roopra A., Saunders D., Shownkeen R., RA Sims M., Smaldon N., Smith A., Smith M., Sonnhammer E., Staden R., RA Sulston J., Thierry-Mieg J., Thomas K., Vaudin M., Vaughan K., RA Waterston R., Watson A., Weinstock L., Wilkinson-Sproat J., RA Wohldman P.; RT "2.2 Mb of contiguous nucleotide sequence from chromosome III of C. RT elegans."; RL Nature 368:32-38(1994). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2; RX MEDLINE=99069613; PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RT "Genome sequence of the nematode C. elegans: a platform for RT investigating biology."; RL Science 282:2012-2018(1998). RN [3] RP FUNCTION, AND SUBCELLULAR LOCATION. RX MEDLINE=23001030; PubMed=12937276; DOI=10.1091/mbc.E03-04-0237; RA Galy V., Mattaj I.W., Askjaer P.; RT "Caenorhabditis elegans nucleoporins Nup93 and Nup205 determine the RT limit of nuclear pore complex size exclusion in vivo."; RL Mol. Biol. Cell 14:5104-5115(2003). CC -!- FUNCTION: Important for early nematode development. CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex. CC -!- SIMILARITY: Belongs to the nucleoporin Nup133 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; FO080706; CCD66018.1; -; Genomic_DNA. DR PIR; S44772; S44772. DR UniGene; Cel.32345; -. DR ProteinModelPortal; P34343; -. DR STRING; P34343; -. DR PRIDE; P34343; -. DR EnsemblMetazoa; C29E4.4; C29E4.4; C29E4.4. DR KEGG; cel:C29E4.4; -. DR UCSC; C29E4.4; c. elegans. DR CTD; 176114; -. DR WormBase; C29E4.4; CE46384; WBGene00003801; npp-15. DR eggNOG; NOG312399; -. DR GeneTree; ENSGT00390000011529; -. DR HOGENOM; HBG382193; -. DR InParanoid; P34343; -. DR KO; K14300; -. DR OMA; FLLTTTS; -. DR PhylomeDB; P34343; -. DR NextBio; 891174; -. DR ArrayExpress; P34343; -. DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell. DR GO; GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase. DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW. DR GO; GO:0040010; P:positive regulation of growth rate; IMP:WormBase. DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW. DR InterPro; IPR007187; Nucleoporin_Nup133/Nup155_C. DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom. DR Gene3D; G3DSA:2.130.10.10; WD40/YVTN_repeat-like; 1. DR Pfam; PF03177; Nucleoporin_C; 1. PE 2: Evidence at transcript level; KW Complete proteome; Developmental protein; mRNA transport; KW Nuclear pore complex; Nucleus; Protein transport; Reference proteome; KW Translocation; Transport. FT CHAIN 1 1129 Nuclear pore complex protein 15. FT /FTId=PRO_0000204840. SQ SEQUENCE 1129 AA; 128190 MW; 8DC884B295983965 CRC64; MSGRDLELTL DRVSSIEYPA LVKEAFLNNW HASAHRSEVT SNCASLNDRY CWVLSRNQIF IWERAKSSHR AIIPTQLPLP TSGLPRSVKC VVVYDGVHRG ANKTPCPGIL VVSPEGVLRH WTSIESQTYI EEVLDINNEV ALRVELTDEP IDGKSASFLL TTTSGTVYFL NGKGQDSAKT GALECNKVAG REAHGFRRRL SSIMFGGESK ESTSLITNSF QHQSKDLLVV TVSPDVLTVY NMYTPCELWS LKTKEFFQPK IASFFEADLK RTPLKVRARL IDAAVFRDGL MILIGGTHEE SQSVHMFMVW MSANWQTEQP TGVVWSARVP MNEHRALFSK IDDSIYSNLT LCIPKNTAES KKADRTDGII IINPYFAVSL YLPFDLAKPK KPESLYRHVS IPPRDQLLGY AICSQYVYIM MLESGVSTIR LLPRGFADSS IYTHEQVVVP SLSVGTDDWP ILSELLSEMV ASGLPKTPLY QSLHRAFELF AEKHMAESEE ELKAIIKMPD QEIARIVSQF LYAIIDYSDA ANKTDTELHA KRVLTSRIML FLKHMGVYER IISSPLGISR GGILSLRVGG TMLGEVSERV AASTAIWTWK TSNETNSAVF DAIIEKVLRI PEVQDLGLKD KDALFGRCGL VHHIPVVAAQ QLEKNVIGKT KSHRFEVFHA VCELLSGIKE TIISWRNCRT KVAIPKFPIW WTLETFASCY RDVAEKIIEE LKNGSSTDSE RARLLMYILS IYDFYLSESD SQPDNDKVLQ EMIALGKPAD AMELAEKHKD FGTLVKNYLT TDVGTRQKTF ERYKKMFEKD DFEMYLCDYL KEHGRNDVLL QQGGSRVDAY LDNFKELRYS REIANKQFGK AALTLMSLAD AETKSFSKFV EFLTRAYYCA CSSIDGTDVS EVLDFYKRRY PEMKHRKRIP TEILKICFGN DLDAMMSVED MLEWNMAVQP NDEASVEGFA RAFHLLADLL AVHPDSDELK KKIDKTWKAL VDYDEWNRVR SKEDVEKKTI FGKFCNYLIN SYPADKGDSF PIWMPISRRL IFPTDIDTVL DECIANTTGN HLSWIKGHLK WIGEQLCKQA LLPKSAFFRP DMKQVGSISQ AALEAFGPIL QRREQRFIDQ LNRDSMMET //