ID NU133_CAEEL Reviewed; 1127 AA. AC P34343; Q5WRU8; DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot. DT 05-JUL-2005, sequence version 3. DT 01-SEP-2009, entry version 59. DE RecName: Full=Nuclear pore complex protein 15; DE AltName: Full=Nucleoporin npp-15; GN Name=npp-15; Synonyms=nup133; ORFNames=C29E4.4; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; OC Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=6239; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2; RX MEDLINE=94150718; PubMed=7906398; DOI=10.1038/368032a0; RA Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., RA Bonfield J., Burton J., Connell M., Copsey T., Cooper J., Coulson A., RA Craxton M., Dear S., Du Z., Durbin R., Favello A., Fraser A., RA Fulton L., Gardner A., Green P., Hawkins T., Hillier L., Jier M., RA Johnston L., Jones M., Kershaw J., Kirsten J., Laisster N., RA Latreille P., Lightning J., Lloyd C., Mortimore B., O'Callaghan M., RA Parsons J., Percy C., Rifken L., Roopra A., Saunders D., Shownkeen R., RA Sims M., Smaldon N., Smith A., Smith M., Sonnhammer E., Staden R., RA Sulston J., Thierry-Mieg J., Thomas K., Vaudin M., Vaughan K., RA Waterston R., Watson A., Weinstock L., Wilkinson-Sproat J., RA Wohldman P.; RT "2.2 Mb of contiguous nucleotide sequence from chromosome III of C. RT elegans."; RL Nature 368:32-38(1994). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2; RX MEDLINE=99069613; PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RT "Genome sequence of the nematode C. elegans: a platform for RT investigating biology."; RL Science 282:2012-2018(1998). RN [3] RP FUNCTION, AND SUBCELLULAR LOCATION. RX MEDLINE=23001030; PubMed=12937276; DOI=10.1091/mbc.E03-04-0237; RA Galy V., Mattaj I.W., Askjaer P.; RT "Caenorhabditis elegans nucleoporins Nup93 and Nup205 determine the RT limit of nuclear pore complex size exclusion in vivo."; RL Mol. Biol. Cell 14:5104-5115(2003). CC -!- FUNCTION: Important for early nematode development. CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex. CC -!- SIMILARITY: Belongs to the nucleoporin Nup133 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L23651; AAU87829.1; -; Genomic_DNA. DR PIR; S44772; S44772. DR RefSeq; NP_498724.3; -. DR UniGene; Cel.32345; -. DR Ensembl; C29E4.4; C29E4.4; C29E4.4; Caenorhabditis elegans. DR GeneID; 176114; -. DR KEGG; cel:C29E4.4; -. DR UCSC; C29E4.4; c. elegans. DR CTD; 176114; -. DR WormBase; WBGene00003801; npp-15. DR WormPep; C29E4.4; CE37484. DR OMA; P34343; NNWHASA. DR NextBio; 891174; -. DR ArrayExpress; P34343; -. DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell. DR GO; GO:0009792; P:embryonic development ending in birth or eg...; IMP:WormBase. DR GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:UniProtKB-KW. DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW. DR InterPro; IPR014908; Nup133_N. DR InterPro; IPR015943; WD40/YVTN_repeat-like. DR Gene3D; G3DSA:2.130.10.10; WD40/YVTN_repeat-like; 1. DR Pfam; PF08801; Nup133_N; 1. PE 2: Evidence at transcript level; KW Complete proteome; Developmental protein; mRNA transport; KW Nuclear pore complex; Nucleus; Protein transport; Translocation; KW Transport. FT CHAIN 1 1127 Nuclear pore complex protein 15. FT /FTId=PRO_0000204840. SQ SEQUENCE 1127 AA; 127945 MW; E85CAEB1A377917D CRC64; MSGRDLELTL DRVSSIEYPA LVKEAFLNNW HASAHRSEVT SNCASLNDRY CWVLSRNQIF IWERAKSSHR AIIPTQLPLP TSGLPRSVKC VVVYDGVHRG ANKTPCPGIL VVSPEGVLRH WTSIESQTYI EEVLDINNEV ALRVELTDEP IDGKSASFLL TTTSGTVYFL NGKGQDSAKT GALECNKVAG REAHGFRRRL SSIMFGGESK ESTSLITNSF QHQSKDLLVV TVSPDVLTVY NMYTPCELWS LKTKEFFQPK IASFFEADLK RTPLKVRARL IDAAVFRDGL MILIGGTHEE SQSVHMFMVW MSANWQTEQP TGVVWSARVP MNEHRALFSK IDDSIYSNLT LCIPKNTAES KKADRTDGII IINPYFAVSL YLPFDLAKPK KPESLYRHVS IPPRDQLLGY AICSQYVYIM MLESGVSTIR LLPRGFADSS IYTHEQVVVP SLSVGTDDWP ILSELLSEMV ASGLPKTPLY QSLHRAFELF AEKHMAESEE ELKAIIKMPD QEIARIVSQF LYAIIDYSDA ANKTDTELHA KRVLTSRIML FLKHMGVYER IISSPLGISR GGILSLRVGG TMLGEVSERV AASTAIWTWK TSNETNSAVF DAIIEKVLRI PEVQDLGLKD KDALFGRCGL VHHIPVVAAQ QLEKNVIGKT KSHRFEVFHA VCELLSGIKE TIISWRKTKV AIPKFPIWWT LETFASCYRD VAEKIIEELK NGSSTDSERA RLLMYILSIY DFYLSESDSQ PDNDKVLQEM IALGKPADAM ELAEKHKDFG TLVKNYLTTD VGTRQKTFER YKKMFEKDDF EMYLCDYLKE HGRNDVLLQQ GGSRVDAYLD NFKELRYSRE IANKQFGKAA LTLMSLADAE TKSFSKFVEF LTRAYYCACS SIDGTDVSEV LDFYKRRYPE MKHRKRIPTE ILKICFGNDL DAMMSVEDML EWNMAVQPND EASVEGFARA FHLLADLLAV HPDSDELKKK IDKTWKALVD YDEWNRVRSK EDVEKKTIFG KFCNYLINSY PADKGDSFPI WMPISRRLIF PTDIDTVLDE CIANTTGNHL SWIKGHLKWI GEQLCKQALL PKSAFFRPDM KQVGSISQAA LEAFGPILQR REQRFIDQLN RDSMMET //