ID P17_DICDI STANDARD; PRT; 146 AA. AC P34121; DT 01-FEB-1994 (Rel. 28, Created) DT 01-FEB-1994 (Rel. 28, Last sequence update) DT 01-NOV-1997 (Rel. 35, Last annotation update) DE Cytoskeletal P17 protein (Coactosin) (Cyclic AMP-regulated protein DE P16). GN P17. OS Dictyostelium discoideum (Slime mold). OC Eukaryota; Mycetozoa; Dictyosteliida; Dictyostelium. OX NCBI_TaxID=44689; RN [1] RP SEQUENCE FROM N.A., AND SEQUENCE OF 128-133. RC STRAIN=AX2; RX MEDLINE=94123348; PubMed=8293475; RA de Hostos E.L., Bradtke B., Lottspeich F., Gerisch G.; RT "Coactosin, a 17 kDa F-actin binding protein from Dictyostelium RT discoideum."; RL Cell Motil. Cytoskeleton 26:181-191(1993). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=AX3; RA Sastry R., Abbruzzi G., Tauber A.I.; RL Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: BINDS TO F-ACTIN IN A CALCIUM INDEPENDENT MANNER. BINDS CC TO THE FILAMENTS ALONG THEIR LENGTH. CC -!- SUBCELLULAR LOCATION: Cytoplasmic. CC -!- PTM: THE N-TERMINUS IS BLOCKED. CC -!- SIMILARITY: SOME, TO DREBRINS, COFILINS, AND YEAST ABP1. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X61797; CAA43899.1; -. DR EMBL; M92992; AAA33174.1; -. DR PIR; S17111; S17111. DR SWISS-2DPAGE; P34121; DICTY. DR DictyDb; DD01050; -. DR InterPro; IPR002108; Actbind_cofln. DR Pfam; PF00241; cofilin_ADF; 1. DR SMART; SM00102; ADF; 1. KW Cytoskeleton; Actin-binding. SQ SEQUENCE 146 AA; 16004 MW; EE7AE2432D8FE1D9 CRC64; MADVSSTELK AAYDEVLADS NDTNWCLFKY EGKNKIVLSG KGSGGFAELA QEINQPSERL YAYLRVVSGD DESKRSKFVF ISWCGEEVGP LAKANVSVHK ASVKQVIKNI GVEVHYTVAD DLNEEELMTK VRKSSGADYS GNKSTN //