ID RANG_MOUSE STANDARD; PRT; 203 AA. AC P34022; P34023; DT 01-FEB-1994 (REL. 28, CREATED) DT 01-FEB-1994 (REL. 28, LAST SEQUENCE UPDATE) DT 01-OCT-1996 (REL. 34, LAST ANNOTATION UPDATE) DE RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN (RAN BINDING PROTEIN 1) DE (RANBP1). GN RANBP1 OR HTF9-A. OS MUS MUSCULUS (MOUSE). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA; OC EUTHERIA; RODENTIA. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 94077185. RA COUTAVAS E., REN M., OPPENHEIM J.D., D'EUSTACHIO P., RUSH M.G.; RL NATURE 366:585-587(1993). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=C57BL; RX MEDLINE; 91365246. RA BRESSAN A., SOMMA M.P., LEWIS J., SANTOLAMAZZA C., COPELAND N.G., RA GILBERT D.J., JENKINS N.A., LAVIA P.; RL GENE 103:201-209(1991). RN [3] RP SEQUENCE FROM N.A. RC STRAIN=C57BL; RA LAVIA P.; RL SUBMITTED (XXX-1994) TO EMBL/GENBANK/DDBJ DATA BANKS. CC -!- FUNCTION: INHIBITS GTP EXCHANGE ON RAN. FORMS A RAN-GTP-RANBP1 CC TRIMERIC COMPLEX. INCREASE GTP HYDROLYSIS INDUCED BY THE RAN CC GTPASE ACTIVATING PROTEIN RANGAP1. MAY ACT IN AN INTRACELLULAR CC SIGNALLING PATHWAY WHICH MAY CONTROL THE PROGRESSION THROUGH THE CC CELL CYCLE BY REGULATING THE TRANSPORT OF PROTEIN AND NUCLEIC CC ACIDS ACROSS THE NUCLEAR MEMBRANE. CC -!- SIMILARITY: TO OTHER EUKARYOTIC RANBP1. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X56046; G444000; -. DR EMBL; L25255; G431422; -. DR EMBL; X56045; G443998; -. DR PIR; JQ1973; JQ1973. KW GTPASE ACTIVATION. FT CONFLICT 9 9 E -> A (IN REF. 2). FT CONFLICT 22 24 NHD -> TTH (IN REF. 2). FT CONFLICT 33 33 V -> L (IN REF. 3). FT CONFLICT 70 72 RGT -> PRH (IN REF. 2). FT CONFLICT 126 126 A -> T (IN REF. 2 AND 3). SQ SEQUENCE 203 AA; 23582 MW; D26C716C CRC32; MAAAKDSHED HDTSTENADE SNHDPQFEPI VSVPEQEIKT LEEDEEELFK MRAKLFRFAS ENDLPEWKER GTGDVKLLKH KEKGTIRLLM RRDKTLKICA NHYITPMMEL KPNAGSDRAW VWNTHADFAD ECPKPELLAI RFLNAENAQK FKTKFEECRK EIEEREKKGP GKNDNAEKVA EKLEALSVRE AREEAEEKSE EKQ //