ID RS12_MYCIT Reviewed; 124 AA. AC P33565; DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot. DT 01-FEB-1994, sequence version 1. DT 10-FEB-2021, entry version 90. DE RecName: Full=30S ribosomal protein S12 {ECO:0000255|HAMAP-Rule:MF_00403}; GN Name=rpsL {ECO:0000255|HAMAP-Rule:MF_00403}; OS Mycobacterium intracellulare. OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; OC Mycobacterium; Mycobacterium avium complex (MAC). OX NCBI_TaxID=1767; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX PubMed=8451173; DOI=10.1093/nar/21.4.1039; RA Nair J., Rouse D.A., Morris S.L.; RT "Nucleotide sequence analysis of the ribosomal S12 gene of Mycobacterium RT intracellulare."; RL Nucleic Acids Res. 21:1039-1039(1993). CC -!- FUNCTION: With S4 and S5 plays an important role in translational CC accuracy. {ECO:0000255|HAMAP-Rule:MF_00403}. CC -!- FUNCTION: Interacts with and stabilizes bases of the 16S rRNA that are CC involved in tRNA selection in the A site and with the mRNA backbone. CC Located at the interface of the 30S and 50S subunits, it traverses the CC body of the 30S subunit contacting proteins on the other side and CC probably holding the rRNA structure together. The combined cluster of CC proteins S8, S12 and S17 appears to hold together the shoulder and CC platform of the 30S subunit. {ECO:0000255|HAMAP-Rule:MF_00403}. CC -!- SUBUNIT: Part of the 30S ribosomal subunit. Contacts proteins S8 and CC S17. May interact with IF1 in the 30S initiation complex. CC {ECO:0000255|HAMAP-Rule:MF_00403}. CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS12 family. CC {ECO:0000255|HAMAP-Rule:MF_00403}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L08171; AAA25375.1; -; Genomic_DNA. DR PIR; S35537; S35537. DR RefSeq; WP_007767794.1; NZ_NSFE01000027.1. DR SMR; P33565; -. DR GeneID; 47815850; -. DR GeneID; 58415393; -. DR GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro. DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro. DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule. DR CDD; cd03368; Ribosomal_S12; 1. DR HAMAP; MF_00403_B; Ribosomal_S12_B; 1. DR InterPro; IPR012340; NA-bd_OB-fold. DR InterPro; IPR006032; Ribosomal_S12/S23. DR InterPro; IPR005679; Ribosomal_S12_bac. DR PANTHER; PTHR11652; PTHR11652; 1. DR Pfam; PF00164; Ribosom_S12_S23; 1. DR PIRSF; PIRSF002133; Ribosomal_S12/S23; 1. DR PRINTS; PR01034; RIBOSOMALS12. DR SUPFAM; SSF50249; SSF50249; 1. DR TIGRFAMs; TIGR00981; rpsL_bact; 1. DR PROSITE; PS00055; RIBOSOMAL_S12; 1. PE 3: Inferred from homology; KW Methylation; Ribonucleoprotein; Ribosomal protein; RNA-binding; KW rRNA-binding; tRNA-binding. FT CHAIN 1..124 FT /note="30S ribosomal protein S12" FT /id="PRO_0000146262" FT MOD_RES 89 FT /note="3-methylthioaspartic acid" FT /evidence="ECO:0000250" SQ SEQUENCE 124 AA; 13849 MW; 8B2D288264B31C3E CRC64; MPTIQQLVRK GRRDKVAKVK TAALKGSPQR RGVCTRVYTT TPKKPNSALR KVARVKLTSQ VEVTAYIPGE GHNLQEHSMV LVRGGRVKDL PGVRYKIIRG SLDTQGVKNR KQARSRYGAK KEKS //