ID RPC6_YEAST Reviewed; 317 AA. AC P32910; DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot. DT 01-OCT-1993, sequence version 1. DT 20-FEB-2007, entry version 51. DE DNA-directed RNA polymerase III 36 kDa polypeptide (EC 2.7.7.6) (C34). GN Name=RPC34; OrderedLocusNames=YNR003C; ORFNames=N2031; OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 26-38 AND RP 214-219. RC STRAIN=S288c / GRF88; RX MEDLINE=93016077; PubMed=1400451; RA Stettler S., Mariotte S., Riva M., Sentenac A., Thuriaux P.; RT "An essential and specific subunit of RNA polymerase III (C) is RT encoded by gene RPC34 in Saccharomyces cerevisiae."; RL J. Biol. Chem. 267:21390-21395(1992). RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=S288c / GRF88; RX MEDLINE=95028151; PubMed=7941739; RA Lalo D., Stettler S., Mariotte S., Gendreau E., Thuriaux P.; RT "Organization of the centromeric region of chromosome XIV in RT Saccharomyces cerevisiae."; RL Yeast 10:523-533(1994). RN [3] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 96604 / S288c / FY1679; RX MEDLINE=95208356; PubMed=7900425; RA Verhasselt P., Aert R., Voet M., Volckaert G.; RT "Twelve open reading frames revealed in the 23.6 kb segment flanking RT the centromere on the Saccharomyces cerevisiae chromosome XIV right RT arm."; RL Yeast 10:1355-1361(1994). RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 96604 / S288c / FY1679; RX MEDLINE=97313269; PubMed=9169873; RA Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., RA Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., RA Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., RA Beinhauer J.D., Boskovic J., Buitrago M.J., Bussereau F., Coster F., RA Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., RA Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., RA Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., RA Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., RA Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., RA Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., RA Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., RA Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., RA Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., RA Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., RA Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., RA Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., RA Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., RA Wambutt R., Wedler H., Zollner A., Hani J.; RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV RT and its evolutionary implications."; RL Nature 387:93-98(1997). CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription CC of DNA into RNA using the four ribonucleoside triphosphates as CC substrates. C34 interacts with TFIIB. CC -!- CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate CC + RNA(n+1). CC -!- SUBUNIT: RNA polymerase III consists of about 15 different CC subunits. CC -!- SUBCELLULAR LOCATION: Nucleus. CC -!- MISCELLANEOUS: Three distinct zinc-containing RNA polymerases are CC found in eukaryotic nuclei: polymerase I for the ribosomal RNA CC precursor, polymerase II for the mRNA precursor, and polymerase CC III for 5S and tRNA genes. CC -!- SIMILARITY: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase CC subunit family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X63746; CAA45278.1; -; Genomic_DNA. DR EMBL; X77395; CAA54572.1; -; Genomic_DNA. DR EMBL; Z71618; CAA96279.1; -; Genomic_DNA. DR PIR; A45107; A45107. DR DIP; DIP:202N; -. DR IntAct; P32910; -. DR Ensembl; YNR003C; Saccharomyces cerevisiae. DR GenomeReviews; Y13139_GR; YNR003C. DR KEGG; sce:YNR003C; -. DR CYGD; YNR003c; -. DR SGD; S000005286; RPC34. DR BioCyc; SCER-S28-01:SCER-S28-01-005202-MONOMER; -. DR LinkHub; P32910; -. DR GermOnline; YNR003C; Saccharomyces cerevisiae. DR GO; GO:0005737; C:cytoplasm; IDA:SGD. DR GO; GO:0005666; C:DNA-directed RNA polymerase III complex; TAS:SGD. DR GO; GO:0003899; F:DNA-directed RNA polymerase activity; TAS:SGD. DR InterPro; IPR007832; RNA_pol_Rpc34. DR PANTHER; PTHR12780; RNA_pol_Rpc34; 1. DR Pfam; PF05158; RNA_pol_Rpc34; 1. KW Complete proteome; Direct protein sequencing; KW DNA-directed RNA polymerase; Nuclear protein; Nucleotidyltransferase; KW Transcription; Transferase. FT CHAIN 1 317 DNA-directed RNA polymerase III 36 kDa FT polypeptide. FT /FTId=PRO_0000073977. SQ SEQUENCE 317 AA; 36135 MW; BDE5CD6FD08BDA7F CRC64; MSGMIENGLQ LSDNAKTLHS QMMSKGIGAL FTQQELQKQM GIGSLTDLMS IVQELLDKNL IKLVKQNDEL KFQGVLESEA QKKATMSAEE ALVYSYIEAS GREGIWSKTI KARTNLHQHV VLKCLKSLES QRYVKSVKSV KFPTRKIYML YSLQPSVDIT GGPWFTDGEL DIEFINSLLT IVWRFISENT FPNGFKNFEN GPKKNVFYAP NVKNYSTTQE ILEFITAAQV ANVELTPSNI RSLCEVLVYD DKLEKVTHDC YRVTLESILQ MNQGEGEPEA GNKALEDEEE FSIFNYFKMF PASKHDKEVV YFDEWTI //