ID RPC6_YEAST STANDARD; PRT; 317 AA. AC P32910; DT 01-OCT-1993 (Rel. 27, Created) DT 01-OCT-1993 (Rel. 27, Last sequence update) DT 25-OCT-2004 (Rel. 45, Last annotation update) DE DNA-directed RNA polymerase III 36 kDa polypeptide (EC 2.7.7.6) (C34). GN Name=RPC34; OrderedLocusNames=YNR003C; ORFNames=N2031; OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932; RN [1] RP SEQUENCE FROM N.A., AND SEQUENCE OF 26-38 AND 214-219. RC STRAIN=S288c / GRF88; RX MEDLINE=93016077; PubMed=1400451; RA Stettler S., Mariotte S., Riva M., Sentenac A., Thuriaux P.; RT "An essential and specific subunit of RNA polymerase III (C) is RT encoded by gene RPC34 in Saccharomyces cerevisiae."; RL J. Biol. Chem. 267:21390-21395(1992). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=S288c / GRF88; RX MEDLINE=95028151; PubMed=7941739; RA Lalo D., Stettler S., Mariotte S., Gendreau E., Thuriaux P.; RT "Organization of the centromeric region of chromosome XIV in RT Saccharomyces cerevisiae."; RL Yeast 10:523-533(1994). RN [3] RP SEQUENCE FROM N.A. RC STRAIN=S288c / FY1679; RX MEDLINE=95208356; PubMed=7900425; RA Verhasselt P., Aert R., Voet M., Volckaert G.; RT "Twelve open reading frames revealed in the 23.6 kb segment flanking RT the centromere on the Saccharomyces cerevisiae chromosome XIV right RT arm."; RL Yeast 10:1355-1361(1994). CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription CC of DNA into RNA using the four ribonucleoside triphosphates as CC substrates. C34 interacts with TFIIB. CC -!- CATALYTIC ACTIVITY: N nucleoside triphosphate = N diphosphate + CC {RNA}(N). CC -!- SUBUNIT: RNA polymerase III consists of about 15 different CC subunits. CC -!- SUBCELLULAR LOCATION: Nuclear. CC -!- MISCELLANEOUS: Three distinct zinc-containing RNA polymerases are CC found in eukaryotic nuclei: polymerase I for the ribosomal RNA CC precursor, polymerase II for the mRNA precursor, and polymerase CC III for 5S and tRNA genes. CC -!- SIMILARITY: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase CC subunit family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X63746; CAA45278.1; -. DR EMBL; X77395; CAA54572.1; -. DR EMBL; Z71618; CAA96279.1; -. DR PIR; A45107; A45107. DR GermOnline; 143348; -. DR SGD; S000005286; RPC34. DR GO; GO:0005737; C:cytoplasm; IDA. DR GO; GO:0005634; C:nucleus; IDA. DR InterPro; IPR007832; RNA_pol_Rpc34. DR InterPro; IPR009058; Wing_hlx_DNA_bnd. DR Pfam; PF05158; RNA_pol_Rpc34; 1. KW Direct protein sequencing; DNA-directed RNA polymerase; KW Nuclear protein; Transcription; Transferase. SQ SEQUENCE 317 AA; 36135 MW; BDE5CD6FD08BDA7F CRC64; MSGMIENGLQ LSDNAKTLHS QMMSKGIGAL FTQQELQKQM GIGSLTDLMS IVQELLDKNL IKLVKQNDEL KFQGVLESEA QKKATMSAEE ALVYSYIEAS GREGIWSKTI KARTNLHQHV VLKCLKSLES QRYVKSVKSV KFPTRKIYML YSLQPSVDIT GGPWFTDGEL DIEFINSLLT IVWRFISENT FPNGFKNFEN GPKKNVFYAP NVKNYSTTQE ILEFITAAQV ANVELTPSNI RSLCEVLVYD DKLEKVTHDC YRVTLESILQ MNQGEGEPEA GNKALEDEEE FSIFNYFKMF PASKHDKEVV YFDEWTI //