ID RPC6_YEAST STANDARD; PRT; 317 AA. AC P32910; DT 01-OCT-1993 (Rel. 27, Created) DT 01-OCT-1993 (Rel. 27, Last sequence update) DT 01-OCT-1996 (Rel. 34, Last annotation update) DE DNA-DIRECTED RNA POLYMERASE III 36 KDA POLYPEPTIDE (EC 2.7.7.6) (C34). GN RPC34 OR YNR003C OR N2031. OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Ascomycota; Saccharomycetes; Saccharomycetales; OC Saccharomycetaceae; Saccharomyces. RN [1] RP SEQUENCE FROM N.A., AND SEQUENCE OF 26-38 AND 214-219. RC STRAIN=GRF88; RX MEDLINE; 93016077. RA Stettler S., Mariotte S., Riva M., Sentenac A., Thuriaux P.; RT "An essential and specific subunit of RNA polymerase III (C) is RT encoded by gene RPC34 in Saccharomyces cerevisiae."; RL J. Biol. Chem. 267:21390-21395(1992). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=GRF88; RX MEDLINE; 95028151. RA Lalo D., Stettler S., Mariotte S., Gendreau E., Thuriaux P.; RT "Organization of the centromeric region of chromosome XIV in RT Saccharomyces cerevisiae."; RL Yeast 10:523-533(1994). RN [3] RP SEQUENCE FROM N.A. RC STRAIN=S288C / FY1679; RX MEDLINE; 95208356. RA Verhasselt P., Aert R., Voet M., Volckaert G.; RT "Twelve open reading frames revealed in the 23.6 kb segment flanking RT the centromere on the Saccharomyces cerevisiae chromosome XIV right RT arm."; RL Yeast 10:1355-1361(1994). CC -!- FUNCTION: DNA-DEPENDENT RNA POLYMERASE CATALYZES THE TRANSCRIPTION CC OF DNA INTO RNA USING THE FOUR RIBONUCLEOSIDE TRIPHOSPHATES AS CC SUBSTRATES. C34 INTERACTS WITH TFIIB. CC -!- CATALYTIC ACTIVITY: N NUCLEOSIDE TRIPHOSPHATE = N PYROPHOSPHATE + CC RNA(N). CC -!- SUBUNIT: RNA POLYMERASE III CONSISTS OF ABOUT 15 DIFFERENT CC SUBUNITS. CC -!- SUBCELLULAR LOCATION: NUCLEAR. CC -!- MISCELLANEOUS: THREE DISTINCT ZINC-CONTAINING RNA POLYMERASES ARE CC FOUND IN EUKARYOTIC NUCLEI: POLYMERASE I FOR THE RIBOSOMAL RNA CC PRECURSOR, POLYMERASE II FOR THE MRNA PRECURSOR, AND POLYMERASE CC III FOR 5S AND TRNA GENES. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X63746; CAA45278.1; -. DR EMBL; X77395; CAA54572.1; -. DR EMBL; Z71618; CAA96279.1; -. DR PIR; A45107; A45107. DR SGD; L0001689; RPC34. KW Transferase; DNA-directed RNA polymerase; Transcription; KW Nuclear protein. SQ SEQUENCE 317 AA; 36135 MW; BDE5CD6FD08BDA7F CRC64; MSGMIENGLQ LSDNAKTLHS QMMSKGIGAL FTQQELQKQM GIGSLTDLMS IVQELLDKNL IKLVKQNDEL KFQGVLESEA QKKATMSAEE ALVYSYIEAS GREGIWSKTI KARTNLHQHV VLKCLKSLES QRYVKSVKSV KFPTRKIYML YSLQPSVDIT GGPWFTDGEL DIEFINSLLT IVWRFISENT FPNGFKNFEN GPKKNVFYAP NVKNYSTTQE ILEFITAAQV ANVELTPSNI RSLCEVLVYD DKLEKVTHDC YRVTLESILQ MNQGEGEPEA GNKALEDEEE FSIFNYFKMF PASKHDKEVV YFDEWTI //