ID GTR3_MOUSE STANDARD; PRT; 493 AA. AC P32037; DT 01-JUL-1993 (Rel. 26, Created) DT 01-JUL-1993 (Rel. 26, Last sequence update) DT 01-NOV-1997 (Rel. 35, Last annotation update) DE GLUCOSE TRANSPORTER TYPE 3, BRAIN. GN SLC2A3 OR GLUT3 OR GLUT-3. OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; OC Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus. RN [1] RP SEQUENCE FROM N.A. RC TISSUE=BRAIN; RX MEDLINE; 92112695. RA NAGAMATSU S., KORNHAUSER J.M., SEINO S., MAYO K.E., STEINER D.F., RA BELL G.I.; RT "Glucose transporter expression in brain. cDNA sequence of mouse RT GLUT3, the brain facilitative glucose transporter isoform, and RT identification of sites of expression by in situ hybridization."; RL J. Biol. Chem. 267:467-472(1992). RN [2] RP SEQUENCE FROM N.A. RA TAKEDA J., MINOKOSHI Y., YASUDA K., KAYANO T., GRAEME B.I.; RL Submitted (JUL-1994) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: FACILITATIVE GLUCOSE TRANSPORTER. PROBABLY A NEURONAL CC GLUCOSE TRANSPORTER. CC -!- SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. CC -!- TISSUE SPECIFICITY: HIGHLY EXPRESSED IN BRAIN. CC -!- SIMILARITY: HIGH TO OTHER GLUCOSE TRANSPORTERS. CC -!- SIMILARITY: BELONGS TO THE SUGAR TRANSPORTER FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M75135; AAA37704.1; -. DR EMBL; X61093; CAA43406.1; -. DR EMBL; U11853; AAB60666.1; -. DR EMBL; U11844; AAB60666.1; JOINED. DR EMBL; U11845; AAB60666.1; JOINED. DR EMBL; U11846; AAB60666.1; JOINED. DR EMBL; U11848; AAB60666.1; JOINED. DR EMBL; U11849; AAB60666.1; JOINED. DR EMBL; U11850; AAB60666.1; JOINED. DR EMBL; U11851; AAB60666.1; JOINED. DR EMBL; U11852; AAB60666.1; JOINED. DR PIR; A41751; A41751. DR MGD; MGI:95757; SLC2A3. DR PFAM; PF00083; sugar_tr; 1. DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1. DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1. KW Duplication; Transmembrane; Sugar transport; Transport; Glycoprotein; KW Multigene family. FT TRANSMEM 11 31 POTENTIAL. FT DOMAIN 32 64 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 65 85 POTENTIAL. FT TRANSMEM 94 114 POTENTIAL. FT TRANSMEM 125 145 POTENTIAL. FT TRANSMEM 154 174 POTENTIAL. FT TRANSMEM 184 204 POTENTIAL. FT DOMAIN 205 269 CYTOPLASMIC (POTENTIAL). FT TRANSMEM 270 290 POTENTIAL. FT TRANSMEM 305 325 POTENTIAL. FT TRANSMEM 336 355 POTENTIAL. FT TRANSMEM 367 387 POTENTIAL. FT TRANSMEM 400 420 POTENTIAL. FT TRANSMEM 428 448 POTENTIAL. FT DOMAIN 449 493 CYTOPLASMIC (POTENTIAL). FT CARBOHYD 43 43 POTENTIAL. SQ SEQUENCE 493 AA; 53478 MW; EEEB8F53 CRC32; MGTTKVTPSL VFAVTVATIG SFQFGYNTGV INAPETILKD FLNYTLEERL EDLPSEGLLT ALWSLCVAIF SVGGMIGSFS VGLFVNRFGR RNSMLLVNLL AIIAGCLMGF AKIAESVEML ILGRLLIGIF CGLCTGFVPM YIGEVSPTAL RGAFGTLNQL GIVVGILVAQ IFGLDFILGS EELWPGLLGL TIIPAILQSA ALPFCPESPR FLLINKKEED QATEILQRLW GTSDVVQEIQ EMKDESVRMS QEKQVTVLEL FRSPNYVQPL LISIVLQLSQ QLSGINAVFY YSTGIFKDAG VQEPIYATIG AGVVNTIFTV VSLFLVERAG RRTLHMIGLG GMAVCSVFMT ISLLLKDDYE AMSFVCIVAI LIYVAFFEIG PGPIPWFIVA ELFSQGPRPA AIAVAGCCNW TSNFLVGMLF PSAAAYLGAY VFIIFAAFLI FFLIFTFFKV PETKGRTFED IARAFEGQAH SGKGPAGVEL NSMQPVKETP GNA //