ID   CHS1_PHAEX              Reviewed;         189 AA.
AC   P30590;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   03-APR-2013, entry version 57.
DE   RecName: Full=Chitin synthase 1;
DE            EC=2.4.1.16;
DE   AltName: Full=Chitin-UDP acetyl-glucosaminyl transferase 1;
DE   Flags: Fragment;
GN   Name=CHS1;
OS   Phaeococcomyces exophialae (Black yeast-like fungus) (Exophiala
OS   exophialae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   mitosporic Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=13202;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1731323; DOI=10.1073/pnas.89.2.519;
RA   Bowen A.R., Chen-Wu J.L.-P., Momany M., Young R., Szaniszlo P.J.,
RA   Robbins P.W.;
RT   "Classification of fungal chitin synthases.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:519-523(1992).
CC   -!- FUNCTION: Plays a major role in cell wall biogenesis.
CC   -!- CATALYTIC ACTIVITY: UDP-N-acetyl-alpha-D-glucosamine + (1,4-(N-
CC       acetyl-beta-D-glucosaminyl))(n) = UDP + (1,4-(N-acetyl-beta-D-
CC       glucosaminyl))(n+1).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the chitin synthase family.
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DR   EMBL; M82952; AAA33634.1; -; Genomic_DNA.
DR   PIR; F38192; F38192.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004100; F:chitin synthase activity; IEA:EC.
DR   GO; GO:0006031; P:chitin biosynthetic process; IEA:InterPro.
DR   InterPro; IPR004834; Chitin_synth.
DR   Pfam; PF01644; Chitin_synth_1; 1.
DR   ProDom; PD002998; Chitin_synth; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Cell wall biogenesis/degradation; Glycosyltransferase;
KW   Membrane; Transferase; Transmembrane.
FT   CHAIN        <1   >189       Chitin synthase 1.
FT                                /FTId=PRO_0000193706.
FT   NON_TER       1      1
FT   NON_TER     189    189
SQ   SEQUENCE   189 AA;  21219 MW;  7383A678A708B22D CRC64;
     EFLFARTMIG VFKNIEYMCN RTSSKTWGKE AWKKIVVCIV SDGRAKINTR TRAVLAGLGV
     YQDGIAKQQV NGKDVTAHIY EYTTQVGLEL KGTQVSLKPR SATPVQLLFC LKEKNQKKIN
     SHRWFFQAFG RVLDPNICVL IDAGTKPGKD SIYQLWKAFD LEPMCGGACG EIKVMLDHGK
     KLYNPLIAT
//