ID CHS1_PHAEX Reviewed; 189 AA. AC P30590; DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot. DT 01-APR-1993, sequence version 1. DT 10-JUN-2008, entry version 41. DE Chitin synthase 1 (EC 2.4.1.16) (Chitin-UDP acetyl-glucosaminyl DE transferase 1) (Fragment). GN Name=CHS1; OS Phaeococcomyces exophialae. OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; OC mitosporic Herpotrichiellaceae; Exophiala. OX NCBI_TaxID=13202; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX MEDLINE=92115692; PubMed=1731323; RA Bowen A.R., Chen-Wu J.L.-P., Momany M., Young R., Szaniszlo P.J., RA Robbins P.W.; RT "Classification of fungal chitin synthases."; RL Proc. Natl. Acad. Sci. U.S.A. 89:519-523(1992). CC -!- FUNCTION: Plays a major role in cell wall biogenesis. CC -!- CATALYTIC ACTIVITY: UDP-N-acetyl-D-glucosamine + (1,4-(N-acetyl- CC beta-D-glucosaminyl))(n) = UDP + (1,4-(N-acetyl-beta-D- CC glucosaminyl))(n+1). CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. CC -!- SIMILARITY: Belongs to the chitin synthase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M82952; AAA33634.1; -; Genomic_DNA. DR PIR; F38192; F38192. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR InterPro; IPR004834; Chitin_synth. DR Pfam; PF01644; Chitin_synth_1; 1. DR ProDom; PD002998; Chitin_synth; 1. PE 3: Inferred from homology; KW Cell wall biogenesis/degradation; Glycosyltransferase; Membrane; KW Transferase; Transmembrane. FT CHAIN <1 >189 Chitin synthase 1. FT /FTId=PRO_0000193706. FT NON_TER 1 1 FT NON_TER 189 189 SQ SEQUENCE 189 AA; 21219 MW; 7383A678A708B22D CRC64; EFLFARTMIG VFKNIEYMCN RTSSKTWGKE AWKKIVVCIV SDGRAKINTR TRAVLAGLGV YQDGIAKQQV NGKDVTAHIY EYTTQVGLEL KGTQVSLKPR SATPVQLLFC LKEKNQKKIN SHRWFFQAFG RVLDPNICVL IDAGTKPGKD SIYQLWKAFD LEPMCGGACG EIKVMLDHGK KLYNPLIAT //