ID TXW5_NAJNA Reviewed; 62 AA. AC P29179; DT 01-DEC-1992, integrated into UniProtKB/Swiss-Prot. DT 01-DEC-1992, sequence version 1. DT 19-JAN-2010, entry version 54. DE RecName: Full=Weak neurotoxin 5; OS Naja naja (Indian cobra). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Lepidosauria; Squamata; Scleroglossa; Serpentes; Colubroidea; OC Elapidae; Elapinae; Naja. OX NCBI_TaxID=35670; RN [1] RP PROTEIN SEQUENCE. RC TISSUE=Venom; RX MEDLINE=91285111; PubMed=2060629; DOI=10.1016/0014-5793(91)80764-T; RA Shafqat J., Siddiqi A.R., Zaidi Z.H., Joernvall H.; RT "Extensive multiplicity of the miscellaneous type of neurotoxins from RT the venom of the cobra Naja naja naja and structural characterization RT of major components."; RL FEBS Lett. 284:70-72(1991). RN [2] RP 3D-STRUCTURE MODELING. RA Bano A., Salim A., Abbasi A., Zaidi Z.H.; RT "3d-structure of a complex of alpha short chain neurotoxin and human RT acetylcholine receptor peptide by homology modeling."; RL Submitted (MAY-2002) to the PDB data bank. CC -!- SUBCELLULAR LOCATION: Secreted. CC -!- TISSUE SPECIFICITY: Expressed by the venom gland. CC -!- SIMILARITY: Belongs to the snake three-finger toxin family. Orphan CC group II subfamily. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR PIR; S15871; S15871. DR PDB; 1LN7; Model; -; A=1-62. DR PDB; 1XVZ; Model; -; A=1-62. DR PDBsum; 1LN7; -. DR PDBsum; 1XVZ; -. DR SMR; P29179; 1-61. DR HOVERGEN; P29179; -. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. DR GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-KW. DR InterPro; IPR003571; Snake_toxin. DR InterPro; IPR018354; Snake_toxin_BS. DR Pfam; PF00087; Toxin_1; 1. DR PROSITE; PS00272; SNAKE_TOXIN; 1. PE 1: Evidence at protein level; KW 3D-structure; Direct protein sequencing; Disulfide bond; Secreted; KW Toxin. FT CHAIN 1 62 Weak neurotoxin 5. FT /FTId=PRO_0000093637. FT DISULFID 3 24 By similarity. FT DISULFID 6 11 By similarity. FT DISULFID 17 40 By similarity. FT DISULFID 44 54 By similarity. FT DISULFID 55 60 By similarity. FT STRAND 2 5 FT STRAND 8 11 FT STRAND 13 16 FT STRAND 23 28 FT STRAND 30 33 FT STRAND 37 43 FT STRAND 48 55 FT STRAND 57 59 SQ SEQUENCE 62 AA; 6943 MW; 2BA3EB6FDF2BDCF9 CRC64; LTCLICPEKY CNKVHTCLNG ENICFKRFNR ILGKRYDLGC AATCPTVKTG IVQCCSTDKC NH //